# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2436976 | 12 | BPR | = | 0.1 | ALA2439925 | ||||||
2. | ALA2436976 | 12 | t1/2 | = | 0.29 | hr | ALA2437699 | hr | Mus musculus | |||
3. | ALA2436976 | 12 | IC50 | = | 0.99 | uM | ALA2437702 | 6.00 | nM | Mus musculus | ||
4. | ALA2436976 | 12 | Vz/F | = | 2.2 | L/Kg | ALA2437698 | L.kg-1 | Mus musculus | |||
5. | ALA2436976 | 12 | CL(app) | = | 5.4 | L/hr/kg | ALA2437697 | mL.min-1.kg-1 | Mus musculus | |||
6. | ALA2436976 | 12 | IC50 | = | 9 | nM | ALA2437703 | 8.05 | nM | Homo sapiens | ||
7. | ALA2436976 | 12 | PPB | = | 98 | % | ALA2437701 | % | Homo sapiens | |||
8. | ALA2436976 | 12 | INH | = | 98 | % | ALA2438981 | % | Homo sapiens | |||
9. | ALA2436976 | 12 | AUC | = | 136 | ug/hr.kg | ALA2437696 | ug/hr.kg | Mus musculus | |||
10. | ALA2436976 | 12 | Cmax | = | 283 | ug/kg | ALA2439926 | ug/kg | Mus musculus | |||
11. | ALA2436976 | 12 | AUC | = | 1840 | ug/L.hr | ALA2437700 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA2436976 | 12 | Cmax | = | 4250 | ug/L | ALA2437695 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
13. | ALA2436976 | 12 | IC50 | > | 30 | uM | ALA2439900 | nM | Homo sapiens | |||
14. | ALA2436976 | 12 | IC50 | > | 30 | uM | ALA2439898 | nM | Homo sapiens | |||
15. | ALA2436976 | 12 | IC50 | > | 30 | uM | ALA2439899 | nM | Homo sapiens | |||
16. | ALA2436976 | 12 | IC50 | 0 | ALA2439119 | Not Determined | Homo sapiens |