# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2436981 | 9 | IC50 | = | 0.43 | uM | ALA2437702 | 6.37 | nM | Mus musculus | ||
2. | ALA2436981 | 9 | t1/2 | = | 1.13 | hr | ALA2437699 | hr | Mus musculus | |||
3. | ALA2436981 | 9 | BPR | = | 1.2 | ALA2439925 | ||||||
4. | ALA2436981 | 9 | IC50 | = | 3.7 | uM | ALA2439900 | 5.43 | nM | Homo sapiens | ||
5. | ALA2436981 | 9 | IC50 | = | 4.2 | uM | ALA2439898 | 5.38 | nM | Homo sapiens | ||
6. | ALA2436981 | 9 | CL(app) | = | 7.1 | L/hr/kg | ALA2437697 | mL.min-1.kg-1 | Mus musculus | |||
7. | ALA2436981 | 9 | Vz/F | = | 11.7 | L/Kg | ALA2437698 | L.kg-1 | Mus musculus | |||
8. | ALA2436981 | 9 | IC50 | = | 13.7 | uM | ALA2439899 | 4.86 | nM | Homo sapiens | ||
9. | ALA2436981 | 9 | IC50 | = | 19 | nM | ALA2437703 | 7.72 | nM | Homo sapiens | ||
10. | ALA2436981 | 9 | IC50 | = | 46 | nM | ALA2439119 | 7.34 | nM | Homo sapiens | ||
11. | ALA2436981 | 9 | INH | = | 98 | % | ALA2438981 | % | Homo sapiens | |||
12. | ALA2436981 | 9 | PPB | = | 98.4 | % | ALA2437701 | % | Homo sapiens | |||
13. | ALA2436981 | 9 | AUC | = | 213 | ug/hr.kg | ALA2437696 | ug/hr.kg | Mus musculus | |||
14. | ALA2436981 | 9 | Cmax | = | 530 | ug/kg | ALA2439926 | ug/kg | Mus musculus | |||
15. | ALA2436981 | 9 | AUC | = | 1400 | ug/L.hr | ALA2437700 | ng.hr.mL-1 | Mus musculus | |||
16. | ALA2436981 | 9 | Cmax | = | 4742 | ug/L | ALA2437695 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus |