# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2436982 | 10 | IC50 | = | 0.12 | uM | ALA2437702 | 6.92 | nM | Mus musculus | ||
2. | ALA2436982 | 10 | t1/2 | = | 1.21 | hr | ALA2437699 | hr | Mus musculus | |||
3. | ALA2436982 | 10 | IC50 | = | 5 | nM | ALA2439119 | 8.30 | nM | Homo sapiens | ||
4. | ALA2436982 | 10 | CL(app) | = | 6.2 | L/hr/kg | ALA2437697 | mL.min-1.kg-1 | Mus musculus | |||
5. | ALA2436982 | 10 | IC50 | = | 7 | nM | ALA2437703 | 8.15 | nM | Homo sapiens | ||
6. | ALA2436982 | 10 | Vz/F | = | 10.7 | L/Kg | ALA2437698 | L.kg-1 | Mus musculus | |||
7. | ALA2436982 | 10 | AUC | = | 83 | ug/hr.kg | ALA2437696 | ug/hr.kg | Mus musculus | |||
8. | ALA2436982 | 10 | PPB | = | 98.8 | % | ALA2437701 | % | Homo sapiens | |||
9. | ALA2436982 | 10 | INH | = | 99 | % | ALA2438981 | % | Homo sapiens | |||
10. | ALA2436982 | 10 | Cmax | = | 314.5 | ug/kg | ALA2439926 | ug/kg | Mus musculus | |||
11. | ALA2436982 | 10 | AUC | = | 1630 | ug/L.hr | ALA2437700 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA2436982 | 10 | Cmax | = | 4823 | ug/L | ALA2437695 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
13. | ALA2436982 | 10 | IC50 | > | 30 | uM | ALA2439900 | nM | Homo sapiens | |||
14. | ALA2436982 | 10 | IC50 | > | 30 | uM | ALA2439898 | nM | Homo sapiens | |||
15. | ALA2436982 | 10 | IC50 | > | 30 | uM | ALA2439899 | nM | Homo sapiens | |||
16. | ALA2436982 | 10 | BPR | 0 | ALA2439925 | BLD |