# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2436983 | 11 | IC50 | = | 0.51 | uM | ALA2437702 | 6.29 | nM | Mus musculus | ||
2. | ALA2436983 | 11 | BPR | = | 1.02 | ALA2439925 | ||||||
3. | ALA2436983 | 11 | t1/2 | = | 1.95 | hr | ALA2437699 | hr | Mus musculus | |||
4. | ALA2436983 | 11 | CL(app) | = | 3.2 | L/hr/kg | ALA2437697 | mL.min-1.kg-1 | Mus musculus | |||
5. | ALA2436983 | 11 | Vz/F | = | 8.92 | L/Kg | ALA2437698 | L.kg-1 | Mus musculus | |||
6. | ALA2436983 | 11 | IC50 | = | 13.2 | uM | ALA2439900 | 4.88 | nM | Homo sapiens | ||
7. | ALA2436983 | 11 | IC50 | = | 21.8 | uM | ALA2439898 | 4.66 | nM | Homo sapiens | ||
8. | ALA2436983 | 11 | IC50 | = | 78 | nM | ALA2437703 | 7.11 | nM | Homo sapiens | ||
9. | ALA2436983 | 11 | INH | = | 97 | % | ALA2438981 | % | Homo sapiens | |||
10. | ALA2436983 | 11 | PPB | = | 97.6 | % | ALA2437701 | % | Homo sapiens | |||
11. | ALA2436983 | 11 | AUC | = | 693 | ug/hr.kg | ALA2437696 | ug/hr.kg | Mus musculus | |||
12. | ALA2436983 | 11 | Cmax | = | 834 | ug/kg | ALA2439926 | ug/kg | Mus musculus | |||
13. | ALA2436983 | 11 | AUC | = | 3150 | ug/L.hr | ALA2437700 | ng.hr.mL-1 | Mus musculus | |||
14. | ALA2436983 | 11 | Cmax | = | 9788 | ug/L | ALA2437695 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
15. | ALA2436983 | 11 | IC50 | > | 30 | uM | ALA2439899 | nM | Homo sapiens | |||
16. | ALA2436983 | 11 | IC50 | 0 | ALA2439119 | Not Determined | Homo sapiens |