# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2441636 | 5a(SS), SAR110068 | Ki | = | 0.97 | nM | ALA2443820 | 9.01 | nM | Macaca mulatta | ||
2. | ALA2441636 | 5a(SS), SAR110068 | logP | = | 1.31 | ALA2443819 | ||||||
3. | ALA2441636 | 5a(SS), SAR110068 | logD | = | 0.15 | ALA2443817 | ||||||
4. | ALA2441636 | 5a(SS), SAR110068 | solubility | = | 1.1 | mg/ml | ALA2443818 | ug.mL-1 | ||||
5. | ALA2441636 | 5a(SS), SAR110068 | solubility | > | 2.5 | mg/ml | ALA2443815 | ug.mL-1 | ||||
6. | ALA2441636 | 5a(SS), SAR110068 | Drug degradation | < | 2 | % | ALA2443816 | % | ||||
7. | ALA2441636 | 5a(SS), SAR110068 | Drug degradation | < | 2 | % | ALA2443813 | % | ||||
8. | ALA2441636 | 5a(SS), SAR110068 | Drug degradation | < | 2 | % | ALA2443814 | % | ||||
9. | ALA2441636 | 5a(SS), SAR110068 | Drug degradation | < | 2 | % | ALA2443812 | % | ||||
10. | ALA2441636 | 5a(SS), SAR110068 | Ki | = | 1 | nM | ALA2443810 | 9.00 | nM | Homo sapiens | ||
11. | ALA2441636 | 5a(SS), SAR110068 | EC50 | = | 0.9 | nM | ALA2443811 | 9.05 | nM | Homo sapiens | ||
12. | ALA2441636 | 5a(SS), SAR110068 | INH | 0 | ALA2443809 | Active | % | Cavia porcellus | ||||
13. | ALA2441636 | 5a(SS), SAR110068 | INH | = | 53 | % | ALA2443808 | % | Homo sapiens | |||
14. | ALA2441636 | 5a(SS), SAR110068 | INH | = | 53 | % | ALA2443806 | % | ||||
15. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443807 | Stable | % | Homo sapiens | ||||
16. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443803 | Stable | % | |||||
17. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443804 | Stable | % | Rattus norvegicus | ||||
18. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443805 | Stable | % | Mus musculus | ||||
19. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443801 | Stable | % | Canis lupus familiaris | ||||
20. | ALA2441636 | 5a(SS), SAR110068 | Stability | 0 | ALA2443802 | Stable | % | Macaca mulatta |