# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2448747 | DNDI2166113 | IC50 | = | 0 | uM | ALA2448754 | 9.72 | nM | Trypanosoma cruzi | ||
2. | ALA2448747 | DNDI2166113 | % inhibition | = | 54.3 | % | ALA2448773 | % | Homo sapiens | |||
3. | ALA2448747 | DNDI2166113 | % inhibition | = | 81.8 | % | ALA2448774 | % | Homo sapiens | |||
4. | ALA2448747 | DNDI2166113 | IC50 | > | 100 | uM | ALA2448775 | nM | Rattus norvegicus | |||
5. | ALA2448747 | DNDI2166113 | IC50 | = | 51.24 | uM | ALA2448775 | 4.29 | nM | Rattus norvegicus | ||
6. | ALA2448747 | DNDI2166113 | IC50 | = | 34.35 | uM | ALA2448775 | 4.46 | nM | Rattus norvegicus | ||
7. | ALA2448747 | DNDI2166113 | IC50 | = | 75.97 | uM | ALA2448775 | 4.12 | nM | Rattus norvegicus | ||
8. | ALA2448747 | DNDI2166113 | IC90 | = | 0 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
9. | ALA2448747 | DNDI2166113 | IC90 | = | 0 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
10. | ALA2448747 | DNDI2166113 | IC90 | = | 0.096 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
11. | ALA2448747 | DNDI2166113 | IC90 | = | 0.018 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
12. | ALA2448747 | DNDI2166113 | IC50 | = | 0 | uM | ALA2448754 | 9.70 | nM | Trypanosoma cruzi | ||
13. | ALA2448747 | DNDI2166113 | IC50 | = | 0 | uM | ALA2448754 | 9.66 | nM | Trypanosoma cruzi | ||
14. | ALA2448747 | DNDI2166113 | IC50 | < | 0 | uM | ALA2448754 | nM | Trypanosoma cruzi | |||
15. | ALA2448747 | DNDI2166113 | IC50 | < | 1 | uM | ALA2448771 | nM | Homo sapiens | |||
16. | ALA2448747 | DNDI2166113 | logD | = | 2.8 | none | ALA2448785 | |||||
17. | ALA2448747 | DNDI2166113 | CLint in vitro | = | 157 | uL/min/mg | ALA2448787 | mL.min-1.g-1 | ||||
18. | ALA2448747 | DNDI2166113 | t (1 / 2) | = | 11 | Min | ALA2448789 | hr | ||||
19. | ALA2448747 | DNDI2166113 | Kinetic | < | 1.6 | ug/ml | ALA2448806 | ug/ml | ||||
20. | ALA2448747 | DNDI2166113 | Kinetic | > | 100 | ug/ml | ALA2448805 | ug/ml |