| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA2448752 | DNDI2174706 | EH | = | 0.82 | none | ALA2448788 | none | ||||
| 2. | ALA2448752 | DNDI2174706 | logD | = | 3.7 | none | ALA2448786 | |||||
| 3. | ALA2448752 | DNDI2174706 | Kinetic | > | 50 | ug/ml | ALA2448805 | ug/ml | ||||
| 4. | ALA2448752 | DNDI2174706 | Kinetic | = | 3.1 | ug/ml | ALA2448806 | ug/ml | ||||
| 5. | ALA2448752 | DNDI2174706 | t (1 / 2) | = | 15 | Min | ALA2448789 | hr | ||||
| 6. | ALA2448752 | DNDI2174706 | CLint in vitro | = | 117 | uL/min/mg | ALA2448787 | mL.min-1.g-1 | ||||
| 7. | ALA2448752 | DNDI2174706 | IC50 | < | 1 | uM | ALA2448771 | nM | Homo sapiens | |||
| 8. | ALA2448752 | DNDI2174706 | IC50 | = | 0.005 | uM | ALA2448754 | 8.28 | nM | Trypanosoma cruzi | ||
| 9. | ALA2448752 | DNDI2174706 | IC50 | = | 0.006 | uM | ALA2448754 | 8.21 | nM | Trypanosoma cruzi | ||
| 10. | ALA2448752 | DNDI2174706 | % inhibition | = | 75.9 | % | ALA2448773 | % | Homo sapiens | |||
| 11. | ALA2448752 | DNDI2174706 | % inhibition | = | 91.9 | % | ALA2448774 | % | Homo sapiens | |||
| 12. | ALA2448752 | DNDI2174706 | IC50 | = | 6.36 | uM | ALA2448775 | 5.20 | nM | Rattus norvegicus | ||
| 13. | ALA2448752 | DNDI2174706 | IC50 | = | 4.16 | uM | ALA2448775 | 5.38 | nM | Rattus norvegicus | ||
| 14. | ALA2448752 | DNDI2174706 | IC90 | = | 0.639 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
| 15. | ALA2448752 | DNDI2174706 | IC90 | = | 0.769 | uM | ALA2448755 | nM | Trypanosoma cruzi | |||
| 16. | ALA2448752 | DNDI2174706 | logD | = | 2.8 | none | ALA2448785 |
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