Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA3099133	27	IC50	=	0.24	uM	ALA3102129	6.62		nM	Homo sapiens
2.	ALA3099133	27	IC50	=	0.04	uM	ALA3102127	7.40		nM	Homo sapiens
3.	ALA3099133	27	IC50	=	0.52	uM	ALA3102023	6.28		nM	Homo sapiens
4.	ALA3099133	27	IC50	=	0.05	uM	ALA3102022	7.30		nM	Homo sapiens
5.	ALA3099133	27	Papp	=	2	ucm/s	ALA3102021			ucm/s	Homo sapiens
6.	ALA3099133	27	Papp	=	2	ucm/s	ALA3102020			ucm/s	Homo sapiens
7.	ALA3099133	27	solubility	=	0.03	mg/ml	ALA3102019			ug.mL-1
8.	ALA3099133	27	solubility	=	0.95	mg/ml	ALA3102018			ug.mL-1
9.	ALA3099133	27	PPB	=	99.3	%	ALA3102016			%	Homo sapiens
10.	ALA3099133	27	pKa	=	3.5		ALA3102017
11.	ALA3099133	27	logD	=	0.4		ALA3102014
12.	ALA3099133	27	Cmax	=	2340	ng/ml	ALA3102015		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
13.	ALA3099133	27	AUC	=	2238	ng.hr/ml	ALA3101516			ng.hr.mL-1	Rattus norvegicus
14.	ALA3099133	27	CL/F	=	75	ml/min.kg	ALA3101517			mL.min-1.kg-1	Rattus norvegicus
15.	ALA3099133	27	t1/2	=	5.1	hr	ALA3101514			hr	Rattus norvegicus
16.	ALA3099133	27	F	=	40	%	ALA3101515			%	Rattus norvegicus
17.	ALA3099133	27	IC50	=	85	nM	ALA3778970	7.07		nM	Homo sapiens
18.	ALA3099133	27	t1/2	=	0.02	hr	ALA3778972			hr	Homo sapiens