# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3109983 | 57 | IC50 | = | 0.03 | uM | ALA3112174 | 7.52 | nM | Homo sapiens | ||
2. | ALA3109983 | 57 | IC50 | = | 0.009 | uM | ALA3112173 | 8.05 | nM | Homo sapiens | ||
3. | ALA3109983 | 57 | IC50 | = | 0.06 | uM | ALA3112172 | 7.22 | nM | Homo sapiens | ||
4. | ALA3109983 | 57 | IC50 | = | 0.08 | uM | ALA3112171 | 7.10 | nM | Homo sapiens | ||
5. | ALA3109983 | 57 | IC50 | = | 16 | uM | ALA3112170 | 4.80 | nM | Homo sapiens | ||
6. | ALA3109983 | 57 | IC50 | = | 1.5 | uM | ALA3112168 | 5.82 | nM | Homo sapiens | ||
7. | ALA3109983 | 57 | IC50 | = | 0.28 | uM | ALA3112167 | 6.55 | nM | Homo sapiens | ||
8. | ALA3109983 | 57 | IC50 | > | 50 | uM | ALA3112166 | nM | Homo sapiens | |||
9. | ALA3109983 | 57 | IC50 | = | 24 | uM | ALA3112165 | 4.62 | nM | Homo sapiens | ||
10. | ALA3109983 | 57 | IC50 | > | 50 | uM | ALA3112164 | nM | Homo sapiens | |||
11. | ALA3109983 | 57 | CLH | < | 65 | ml/min.kg | ALA3112163 | mL.min-1.kg-1 | ||||
12. | ALA3109983 | 57 | CLH | = | 40 | ml/min.kg | ALA3112162 | mL.min-1.kg-1 | Homo sapiens | |||
13. | ALA3109983 | 57 | Ratio | = | 4.1 | ALA3112161 | ||||||
14. | ALA3109983 | 57 | Papp | = | 130 | nm/s | ALA3112160 | nm/s | ||||
15. | ALA3109983 | 57 | F | = | 62 | % | ALA3111813 | % | Mus musculus | |||
16. | ALA3109983 | 57 | AUC/dose | = | 1000 | nM.hr.kg/mg | ALA3111812 | nM.hr.kg/mg | Mus musculus | |||
17. | ALA3109983 | 57 | AUC/dose | = | 17 | nM.hr.kg/mg | ALA3111810 | nM.hr.kg/mg | Mus musculus | |||
18. | ALA3109983 | 57 | AUC/dose | = | 1000 | nM.hr.kg/mg | ALA3111811 | nM.hr.kg/mg | Mus musculus | |||
19. | ALA3109983 | 57 | Cmax normalised | = | 280 | nM.kg/mg | ALA3111808 | nM.kg/mg | Mus musculus | |||
20. | ALA3109983 | 57 | Cmax normalised | = | 5.7 | nM.kg/mg | ALA3111807 | nM.kg/mg | Mus musculus |