# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3109985 | 59 | IC50 | = | 0.04 | uM | ALA3112174 | 7.40 | nM | Homo sapiens | ||
2. | ALA3109985 | 59 | IC50 | = | 0.3 | uM | ALA3112167 | 6.52 | nM | Homo sapiens | ||
3. | ALA3109985 | 59 | IC50 | > | 50 | uM | ALA3112166 | nM | Homo sapiens | |||
4. | ALA3109985 | 59 | CLH | = | 71 | ml/min.kg | ALA3112163 | mL.min-1.kg-1 | ||||
5. | ALA3109985 | 59 | CLH | < | 36 | ml/min.kg | ALA3112162 | mL.min-1.kg-1 | Homo sapiens | |||
6. | ALA3109985 | 59 | Ratio | = | 4 | ALA3112161 | ||||||
7. | ALA3109985 | 59 | Papp | = | 255 | nm/s | ALA3112160 | nm/s | ||||
8. | ALA3109985 | 59 | F | = | 73 | % | ALA3111813 | % | Mus musculus | |||
9. | ALA3109985 | 59 | AUC/dose | = | 1500 | nM.hr.kg/mg | ALA3111812 | nM.hr.kg/mg | Mus musculus | |||
10. | ALA3109985 | 59 | AUC/dose | = | 390 | nM.hr.kg/mg | ALA3111810 | nM.hr.kg/mg | Mus musculus | |||
11. | ALA3109985 | 59 | AUC/dose | = | 1000 | nM.hr.kg/mg | ALA3111811 | nM.hr.kg/mg | Mus musculus | |||
12. | ALA3109985 | 59 | Cmax normalised | = | 810 | nM.kg/mg | ALA3111808 | nM.kg/mg | Mus musculus | |||
13. | ALA3109985 | 59 | Cmax normalised | = | 200 | nM.kg/mg | ALA3111807 | nM.kg/mg | Mus musculus | |||
14. | ALA3109985 | 59 | Cmax normalised | = | 420 | nM.kg/mg | ALA3111809 | nM.kg/mg | Mus musculus | |||
15. | ALA3109985 | 59 | BPR | = | 0.3 | ALA3111806 | ||||||
16. | ALA3109985 | 59 | Ratio | = | 0.4 | ALA3111805 | ||||||
17. | ALA3109985 | 59 | CL | = | 1.4 | L/hr/kg | ALA3111804 | mL.min-1.kg-1 | Mus musculus | |||
18. | ALA3109985 | 59 | Vdss | = | 1.6 | L/Kg | ALA3111803 | L.kg-1 | Mus musculus | |||
19. | ALA3109985 | 59 | beta t1/2 | = | 1.7 | hr | ALA3111801 | hr | Mus musculus | |||
20. | ALA3109985 | 59 | IC50 | = | 23 | uM | ALA3111802 | 4.64 | nM | Homo sapiens |