# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3110021 | 31 | IC50 | = | 0.2 | uM | ALA5225333 | 6.70 | nM | Homo sapiens | ||
2. | ALA3110021 | 31 | IC50 | = | 0.02 | uM | ALA3112174 | 7.70 | nM | Homo sapiens | ||
3. | ALA3110021 | 31 | IC50 | = | 0.004 | uM | ALA3112173 | 8.40 | nM | Homo sapiens | ||
4. | ALA3110021 | 31 | IC50 | = | 0.03 | uM | ALA3112172 | 7.52 | nM | Homo sapiens | ||
5. | ALA3110021 | 31 | IC50 | = | 0.04 | uM | ALA3112171 | 7.40 | nM | Homo sapiens | ||
6. | ALA3110021 | 31 | IC50 | = | 12 | uM | ALA3112170 | 4.92 | nM | Homo sapiens | ||
7. | ALA3110021 | 31 | IC50 | = | 0.36 | uM | ALA3112168 | 6.44 | nM | Homo sapiens | ||
8. | ALA3110021 | 31 | IC50 | = | 0.22 | uM | ALA3112167 | 6.66 | nM | Homo sapiens | ||
9. | ALA3110021 | 31 | IC50 | > | 50 | uM | ALA3112166 | nM | Homo sapiens | |||
10. | ALA3110021 | 31 | IC50 | = | 32 | uM | ALA3112165 | 4.50 | nM | Homo sapiens | ||
11. | ALA3110021 | 31 | IC50 | = | 43 | uM | ALA3112164 | 4.37 | nM | Homo sapiens | ||
12. | ALA3110021 | 31 | CLH | = | 89 | ml/min.kg | ALA3112163 | mL.min-1.kg-1 | ||||
13. | ALA3110021 | 31 | CLH | < | 36 | ml/min.kg | ALA3112162 | mL.min-1.kg-1 | Homo sapiens | |||
14. | ALA3110021 | 31 | Ratio | = | 2.4 | ALA3112161 | ||||||
15. | ALA3110021 | 31 | Papp | = | 442 | nm/s | ALA3112160 | nm/s | ||||
16. | ALA3110021 | 31 | Ratio IC50 | = | 2000 | ALA3112158 | ||||||
17. | ALA3110021 | 31 | Ratio IC50 | < | 20 | ALA3111815 | ||||||
18. | ALA3110021 | 31 | F | = | 84 | % | ALA3111813 | % | Mus musculus | |||
19. | ALA3110021 | 31 | AUC/dose | = | 1300 | nM.hr.kg/mg | ALA3111812 | nM.hr.kg/mg | Mus musculus | |||
20. | ALA3110021 | 31 | AUC/dose | = | 700 | nM.hr.kg/mg | ALA3111810 | nM.hr.kg/mg | Mus musculus |