| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3125160 | 3p-(S) | IC50 | = | 6.8 | nM | ALA3128640 | 8.17 | nM | Homo sapiens | ||
| 2. | ALA3125160 | 3p-(S) | solubility | = | 125 | ug ml-1 | ALA3128641 | ug.mL-1 | ||||
| 3. | ALA3125160 | 3p-(S) | solubility | = | 169 | ug ml-1 | ALA3128642 | ug.mL-1 | ||||
| 4. | ALA3125160 | 3p-(S) | logD | = | 1.81 | ALA3128643 | ||||||
| 5. | ALA3125160 | 3p-(S) | t1/2 | = | 8.4 | hr | ALA3128644 | hr | Macaca fascicularis | |||
| 6. | ALA3125160 | 3p-(S) | t1/2 | = | 7.5 | hr | ALA3128645 | hr | Canis lupus familiaris | |||
| 7. | ALA3125160 | 3p-(S) | t1/2 | = | 4.9 | hr | ALA3128646 | hr | Rattus norvegicus | |||
| 8. | ALA3125160 | 3p-(S) | Vdss | = | 0.4 | L/Kg | ALA3128647 | L.kg-1 | Macaca fascicularis | |||
| 9. | ALA3125160 | 3p-(S) | Vdss | = | 0.51 | L/Kg | ALA3128649 | L.kg-1 | Canis lupus familiaris | |||
| 10. | ALA3125160 | 3p-(S) | Vdss | = | 0.21 | L/Kg | ALA3128648 | L.kg-1 | Rattus norvegicus | |||
| 11. | ALA3125160 | 3p-(S) | CL | = | 3.7 | ml/min.kg | ALA3128650 | mL.min-1.kg-1 | Macaca fascicularis | |||
| 12. | ALA3125160 | 3p-(S) | CL | = | 2.8 | ml/min.kg | ALA3128652 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 13. | ALA3125160 | 3p-(S) | CL | = | 0.87 | ml/min.kg | ALA3128651 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA3125160 | 3p-(S) | F | = | 41 | % | ALA3128653 | % | Macaca fascicularis | |||
| 15. | ALA3125160 | 3p-(S) | F | = | 56 | % | ALA3128654 | % | Canis lupus familiaris | |||
| 16. | ALA3125160 | 3p-(S) | F | = | 86 | % | ALA3128655 | % | Rattus norvegicus | |||
| 17. | ALA3125160 | 3p-(S) | AUC | = | 15.7 | uM.hr | ALA3128656 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Macaca fascicularis | ||
| 18. | ALA3125160 | 3p-(S) | AUC | = | 8.4 | uM.hr | ALA3128657 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Canis lupus familiaris | ||
| 19. | ALA3125160 | 3p-(S) | AUC | = | 335 | uM.hr | ALA3128658 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 20. | ALA3125160 | 3p-(S) | CLH | = | 1.3 | ml/min | ALA3128659 | ml/min | Homo sapiens |
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