# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3127661 | 3e | IC50 | = | 37 | nM | ALA3130898 | 7.43 | nM | Rattus norvegicus | ||
2. | ALA3127661 | 3e | IC50 | = | 15 | nM | ALA3130897 | 7.82 | nM | Homo sapiens | ||
3. | ALA3127661 | 3e | Activity | = | -2.1 | g | ALA3130893 | g | Mus musculus | |||
4. | ALA3127661 | 3e | Vd | = | 0.52 | L/Kg | ALA3130892 | L.kg-1 | Rattus norvegicus | |||
5. | ALA3127661 | 3e | CL | = | 3.3 | ml/min.kg | ALA3130891 | mL.min-1.kg-1 | Rattus norvegicus | |||
6. | ALA3127661 | 3e | Cmax | = | 4.4 | ug ml-1 | ALA3130890 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA3127661 | 3e | AUC | = | 38.8 | hr.microg/ml | ALA3130889 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA3127661 | 3e | Cmax | = | 1.6 | ug ml-1 | ALA3130888 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
9. | ALA3127661 | 3e | AUC | = | 10.8 | hr.microg/ml | ALA3130887 | ng.hr.mL-1 | Rattus norvegicus | |||
10. | ALA3127661 | 3e | F | = | 105 | % | ALA3130886 | % | Rattus norvegicus | |||
11. | ALA3127661 | 3e | F | = | 11 | % | ALA3130885 | % | Rattus norvegicus | |||
12. | ALA3127661 | 3e | Activity | = | 42 | g | ALA3130884 | g | Rattus norvegicus | |||
13. | ALA3127661 | 3e | Activity | = | 44 | g | ALA3130883 | g | Rattus norvegicus | |||
14. | ALA3127661 | 3e | Activity | = | 29 | g | ALA3130882 | g | Rattus norvegicus | |||
15. | ALA3127661 | 3e | Activity | = | 80 | g | ALA3130881 | g | Rattus norvegicus | |||
16. | ALA3127661 | 3e | Activity | = | 80 | g | ALA3130880 | g | Rattus norvegicus | |||
17. | ALA3127661 | 3e | Activity | = | 57 | g | ALA3130879 | g | Rattus norvegicus | |||
18. | ALA3127661 | 3e | Activity | = | 116 | g | ALA3130878 | g | Rattus norvegicus | |||
19. | ALA3127661 | 3e | Activity | = | 112 | g | ALA3130877 | g | Rattus norvegicus | |||
20. | ALA3127661 | 3e | Activity | = | 72 | g | ALA3130876 | g | Rattus norvegicus |