| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3127986 | 6h | Activity | = | 27.5 | mmol/L | ALA3131005 | mmol/L | Mus musculus | |||
| 2. | ALA3127986 | 6h | F | = | 37.8 | % | ALA3130761 | % | Rattus norvegicus | |||
| 3. | ALA3127986 | 6h | Activity | = | 38 | mmol/L | ALA3130791 | mmol/L | Mus musculus | |||
| 4. | ALA3127986 | 6h | Activity | = | 41.3 | mmol/L | ALA3131001 | mmol/L | Mus musculus | |||
| 5. | ALA3127986 | 6h | Activity | = | 45.1 | mmol/L | ALA3131006 | mmol/L | Mus musculus | |||
| 6. | ALA3127986 | 6h | IC50 | = | 176.6 | uM | ALA3130759 | nM | Homo sapiens | |||
| 7. | ALA3127986 | 6h | Ratio IC50 | = | 375 | ALA3128753 | ||||||
| 8. | ALA3127986 | 6h | Ratio IC50 | = | 450 | ALA3128752 | ||||||
| 9. | ALA3127986 | 6h | Cmax | = | 2711 | ng/ml | ALA3130783 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3127986 | 6h | AUCt | = | 2731 | ng/mL.hr | ALA3130779 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA3127986 | 6h | AUC | = | 2838 | ng/mL.hr | ALA3130775 | ng.hr.mL-1 | Rattus norvegicus | |||
| 12. | ALA3127986 | 6h | AUCt | = | 2889 | ng/mL.hr | ALA3130778 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA3127986 | 6h | AUC | = | 2896 | ng/mL.hr | ALA3130774 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA3127986 | 6h | Cmax | = | 2957 | ng/ml | ALA3130782 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 15. | ALA3127986 | 6h | INH | 0 | ALA3128751 | Not Active | % | Homo sapiens | ||||
| 16. | ALA3127986 | 6h | INH | 0 | ALA3128749 | Active | % | Homo sapiens | ||||
| 17. | ALA3127986 | 6h | Activity | 0 | ALA3131008 | Dose-dependent effect | Mus musculus | |||||
| 18. | ALA3127986 | 6h | Ki | = | 0.004 | uM | ALA3131012 | 8.46 | nM | Homo sapiens | ||
| 19. | ALA3127986 | 6h | IC50 | = | 0.004 | uM | ALA3128756 | 8.40 | nM | Homo sapiens | ||
| 20. | ALA3127986 | 6h | Tmax | = | 0.3 | hr | ALA3130787 | hr | Rattus norvegicus |
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