| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3127992 | 6n | IC50 | = | 48 | uM | ALA3130759 | 4.32 | nM | Homo sapiens | ||
| 2. | ALA3127992 | 6n | Ratio IC50 | = | 470 | ALA3128752 | ||||||
| 3. | ALA3127992 | 6n | Ratio IC50 | = | 750 | ALA3128753 | ||||||
| 4. | ALA3127992 | 6n | AUCt | = | 1291 | ng/mL.hr | ALA3130777 | ng.hr.mL-1 | Rattus norvegicus | |||
| 5. | ALA3127992 | 6n | AUC | = | 1581 | ng/mL.hr | ALA3130773 | ng.hr.mL-1 | Rattus norvegicus | |||
| 6. | ALA3127992 | 6n | AUCt | = | 1918 | ng/mL.hr | ALA3130776 | ng.hr.mL-1 | Rattus norvegicus | |||
| 7. | ALA3127992 | 6n | AUC | = | 1918 | ng/mL.hr | ALA3130772 | ng.hr.mL-1 | Rattus norvegicus | |||
| 8. | ALA3127992 | 6n | Cmax | = | 2027 | ng/ml | ALA3130780 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 9. | ALA3127992 | 6n | Cmax | = | 2204 | ng/ml | ALA3130781 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3127992 | 6n | INH | 0 | ALA3128748 | Active | % | Homo sapiens | ||||
| 11. | ALA3127992 | 6n | INH | 0 | ALA3128750 | Not Active | % | Homo sapiens | ||||
| 12. | ALA3127992 | 6n | Activity | 0 | ALA3131008 | Dose-dependent effect | Mus musculus | |||||
| 13. | ALA3127992 | 6n | Activity | 0 | ALA3128757 | Dose-dependent effect | Mus musculus | |||||
| 14. | ALA3127992 | 6n | INH | = | -20.3 | % | ALA3130756 | % | Homo sapiens | |||
| 15. | ALA3127992 | 6n | Ki | = | 0.009 | uM | ALA3131012 | 8.05 | nM | Homo sapiens | ||
| 16. | ALA3127992 | 6n | IC50 | = | 0.01 | uM | ALA3128756 | 8.00 | nM | Homo sapiens | ||
| 17. | ALA3127992 | 6n | Tmax | = | 0.3 | hr | ALA3130785 | hr | Rattus norvegicus | |||
| 18. | ALA3127992 | 6n | Tmax | = | 0.3 | hr | ALA3130784 | hr | Rattus norvegicus | |||
| 19. | ALA3127992 | 6n | MRT | = | 0.55 | hr | ALA3130768 | hr | Rattus norvegicus | |||
| 20. | ALA3127992 | 6n | t1/2 | = | 0.63 | hr | ALA3130764 | hr | Rattus norvegicus |
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