# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3137480 | DNDI1724344 | Inhibition | = | 0 | % | ALA3137489 | % | Trypanosoma cruzi | |||
2. | ALA3137480 | DNDI1724344 | IC50 | > | 10 | uM | ALA3137504 | nM | Trypanosoma brucei rhodesiense | |||
3. | ALA3137480 | DNDI1724344 | IC90 | > | 0.1 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
4. | ALA3137480 | DNDI1724344 | IC90 | = | 0.021 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
5. | ALA3137480 | DNDI1724344 | IC50 | > | 100 | uM | ALA3137503 | nM | Rattus norvegicus | |||
6. | ALA3137480 | DNDI1724344 | IC50 | = | 48.07 | uM | ALA3137503 | 4.32 | nM | Rattus norvegicus | ||
7. | ALA3137480 | DNDI1724344 | IC50 | = | 0.016 | uM | ALA3137484 | 7.80 | nM | Trypanosoma cruzi | ||
8. | ALA3137480 | DNDI1724344 | IC50 | = | 0.01 | uM | ALA3137484 | 8.00 | nM | Trypanosoma cruzi | ||
9. | ALA3137480 | DNDI1724344 | IC50 | = | 9 | uM | ALA3137501 | 5.05 | nM | Homo sapiens | ||
10. | ALA3137480 | DNDI1724344 | CLint | = | 32.3 | uL/min/mg | ALA3137517 | mL.min-1.g-1 | ||||
11. | ALA3137480 | DNDI1724344 | t (1 / 2) | = | 53.7 | min | ALA3137515 | hr | ||||
12. | ALA3137480 | DNDI1724344 | logD | = | 4.4 | ALA3137509 | ||||||
13. | ALA3137480 | DNDI1724344 | Kinetic | = | 1.6 | ug/ml | ALA3137532 | ug/ml | ||||
14. | ALA3137480 | DNDI1724344 | Kinetic | = | 1.6 | ug/ml | ALA3137534 | ug/ml | ||||
15. | ALA3137480 | DNDI1724344 | logD | = | 4.3 | ALA3137510 | ||||||
16. | ALA3137480 | DNDI1724344 | EH | = | 0.64 | ALA3137516 |