# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3137481 | DNDI1724945 | IC90 | > | 10 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
2. | ALA3137481 | DNDI1724945 | IC50 | = | 51.5 | uM | ALA3137503 | 4.29 | nM | Rattus norvegicus | ||
3. | ALA3137481 | DNDI1724945 | IC50 | = | 0.036 | uM | ALA3137484 | 7.44 | nM | Trypanosoma cruzi | ||
4. | ALA3137481 | DNDI1724945 | IC50 | > | 20 | uM | ALA3137501 | nM | Homo sapiens | |||
5. | ALA3137481 | DNDI1724945 | CLint | = | 58.2 | uL/min/mg | ALA3137517 | mL.min-1.g-1 | ||||
6. | ALA3137481 | DNDI1724945 | t (1 / 2) | = | 29.8 | min | ALA3137515 | hr | ||||
7. | ALA3137481 | DNDI1724945 | logD | = | 1.6 | ALA3137509 | ||||||
8. | ALA3137481 | DNDI1724945 | Kinetic | > | 100 | ug/ml | ALA3137532 | ug/ml | ||||
9. | ALA3137481 | DNDI1724945 | Kinetic | = | 25 | ug/ml | ALA3137534 | ug/ml | ||||
10. | ALA3137481 | DNDI1724945 | logD | = | 3.9 | ALA3137510 | ||||||
11. | ALA3137481 | DNDI1724945 | EH | = | 0.76 | ALA3137516 |