# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3137482 | DNDI1729593 | IC50 | > | 10 | uM | ALA3137504 | nM | Trypanosoma brucei rhodesiense | |||
2. | ALA3137482 | DNDI1729593 | IC90 | = | 0.025 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
3. | ALA3137482 | DNDI1729593 | IC50 | = | 64.87 | uM | ALA3137503 | 4.19 | nM | Rattus norvegicus | ||
4. | ALA3137482 | DNDI1729593 | IC50 | = | 0.015 | uM | ALA3137484 | 7.82 | nM | Trypanosoma cruzi | ||
5. | ALA3137482 | DNDI1729593 | IC50 | = | 16 | uM | ALA3137501 | 4.80 | nM | Homo sapiens | ||
6. | ALA3137482 | DNDI1729593 | CLint | = | 138.1 | uL/min/mg | ALA3137517 | mL.min-1.g-1 | ||||
7. | ALA3137482 | DNDI1729593 | t (1 / 2) | = | 12.6 | min | ALA3137515 | hr | ||||
8. | ALA3137482 | DNDI1729593 | logD | = | 1.8 | ALA3137509 | ||||||
9. | ALA3137482 | DNDI1729593 | Kinetic | > | 100 | ug/ml | ALA3137532 | ug/ml | ||||
10. | ALA3137482 | DNDI1729593 | Kinetic | = | 3.1 | ug/ml | ALA3137534 | ug/ml | ||||
11. | ALA3137482 | DNDI1729593 | logD | = | 5.1 | ALA3137510 | ||||||
12. | ALA3137482 | DNDI1729593 | EH | = | 0.89 | ALA3137516 |