# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3137483 | DNDI1729594 | IC50 | > | 10 | uM | ALA3137504 | nM | Trypanosoma brucei rhodesiense | |||
2. | ALA3137483 | DNDI1729594 | IC90 | = | 8.139 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
3. | ALA3137483 | DNDI1729594 | IC90 | = | 8.14 | uM | ALA3137485 | nM | Trypanosoma cruzi | |||
4. | ALA3137483 | DNDI1729594 | IC50 | > | 100 | uM | ALA3137503 | nM | Rattus norvegicus | |||
5. | ALA3137483 | DNDI1729594 | IC50 | > | 100 | uM | ALA3137503 | nM | Rattus norvegicus | |||
6. | ALA3137483 | DNDI1729594 | IC50 | = | 5.131 | uM | ALA3137484 | 5.29 | nM | Trypanosoma cruzi | ||
7. | ALA3137483 | DNDI1729594 | IC50 | = | 5.13 | uM | ALA3137484 | 5.29 | nM | Trypanosoma cruzi | ||
8. | ALA3137483 | DNDI1729594 | IC50 | > | 20 | uM | ALA3137501 | nM | Homo sapiens | |||
9. | ALA3137483 | DNDI1729594 | CLint | = | 27.7 | uL/min/mg | ALA3137517 | mL.min-1.g-1 | ||||
10. | ALA3137483 | DNDI1729594 | t (1 / 2) | = | 62.6 | min | ALA3137515 | hr | ||||
11. | ALA3137483 | DNDI1729594 | logD | > | 5.3 | ALA3137509 | ||||||
12. | ALA3137483 | DNDI1729594 | Kinetic | > | 100 | ug/ml | ALA3137532 | ug/ml | ||||
13. | ALA3137483 | DNDI1729594 | Kinetic | = | 1.6 | ug/ml | ALA3137534 | ug/ml | ||||
14. | ALA3137483 | DNDI1729594 | logD | > | 5.3 | ALA3137510 | ||||||
15. | ALA3137483 | DNDI1729594 | EH | = | 0.61 | ALA3137516 |