# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | 12.8 | % | ALA4296184 | Average; N=2 | % | Staphylococcus aureus | ||
2. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | 21.79 | % | ALA4296188 | Average; N=2 | % | Acinetobacter baumannii | ||
3. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | 11.27 | % | ALA4296187 | Average; N=2 | % | Pseudomonas aeruginosa | ||
4. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | 9.44 | % | ALA4296186 | Average; N=2 | % | Klebsiella pneumoniae | ||
5. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | -3.23 | % | ALA4296185 | Average; N=2 | % | Escherichia coli | ||
6. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | -7.65 | % | ALA4296190 | Average; N=2 | % | Cryptococcus neoformans | ||
7. | (±)-Nornicotine | 6 (nornicotine) | Inhibition | = | 3.55 | % | ALA4296189 | Average; N=2 | % | Candida albicans | ||
8. | (±)-Nornicotine | 6 (nornicotine) | EC50 | = | 17.4 | umol/L | ALA4676868 | 4.76 | nM | Rattus norvegicus | ||
9. | (±)-Nornicotine | 6 (nornicotine) | EC50 | = | 375 | umol/L | ALA4676867 | nM | Rattus norvegicus | |||
10. | (±)-Nornicotine | 6 (nornicotine) | EC50 | = | 614 | umol/L | ALA4676866 | nM | Rattus norvegicus | |||
11. | (±)-Nornicotine | 6 (nornicotine) | pKa | = | 9 | ALA3075137 | ||||||
12. | (±)-Nornicotine | 6 (nornicotine) | FC | = | 0.3 | ALA3075138 | Musca domestica | |||||
13. | (±)-Nornicotine | 6 (nornicotine) | IC50 | = | 9.7 | mM | ALA3075136 | nM | Musca domestica | |||
14. | (±)-Nornicotine | 6 (nornicotine) | Ki | = | 8.77 | uM | ALA3075135 | 5.06 | nM | Musca domestica | ||
15. | (±)-Nornicotine | 6 (nornicotine) | Ki | = | 7.61 | uM | ALA3075134 | 5.12 | nM | |||
16. | (±)-Nornicotine | 6 (nornicotine) | pKa | = | 8.76 | ALA3069124 | ||||||
17. | (±)-Nornicotine | 6 (nornicotine) | Ki | = | 30 | nM | ALA885365 | 7.52 | nM | Rattus norvegicus | ||
18. | (±)-Nornicotine | 6 (nornicotine) | Potency | 12.589 | uM | ALA1738442 | inconclusive | nM | Homo sapiens | |||
19. | (±)-Nornicotine | 6 (nornicotine) | Kd | = | 1.06 | nM | ALA830079 | 8.97 | nM | Homo sapiens | ||
20. | (±)-Nornicotine | 6 (nornicotine) | Ki | = | 138000 | nM | ALA830082 | nM | Homo sapiens |