# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3219143 | 10, PF-4776548 | Activity | 0 | ALA3226190 | Not Active | ||||||
2. | ALA3219143 | 10, PF-4776548 | Drug metabolism | 0 | ALA3226191 | Active | ||||||
3. | ALA3219143 | 10, PF-4776548 | t1/2 | = | 2.8 | hr | ALA3226192 | hr | Homo sapiens | |||
4. | ALA3219143 | 10, PF-4776548 | Vdss | = | 5.7 | L/Kg | ALA3226193 | L.kg-1 | Homo sapiens | |||
5. | ALA3219143 | 10, PF-4776548 | CL | = | 18 | ml/min.kg | ALA3226534 | mL.min-1.kg-1 | Homo sapiens | |||
6. | ALA3219143 | 10, PF-4776548 | t1/2 | = | 1.2 | hr | ALA3226535 | hr | Canis lupus familiaris | |||
7. | ALA3219143 | 10, PF-4776548 | Vdss | = | 2 | L/Kg | ALA3226536 | L.kg-1 | Canis lupus familiaris | |||
8. | ALA3219143 | 10, PF-4776548 | CL | = | 24 | ml/min/mg | ALA3226537 | mL.min-1.g-1 | Canis lupus familiaris | |||
9. | ALA3219143 | 10, PF-4776548 | F | = | 1 | % | ALA3226538 | % | Rattus norvegicus | |||
10. | ALA3219143 | 10, PF-4776548 | t1/2 | = | 0.3 | hr | ALA3226539 | hr | Rattus norvegicus | |||
11. | ALA3219143 | 10, PF-4776548 | Vdss | = | 3 | L/Kg | ALA3226540 | L.kg-1 | Rattus norvegicus | |||
12. | ALA3219143 | 10, PF-4776548 | CL | = | 98 | ml/min/mg | ALA3226541 | mL.min-1.g-1 | Rattus norvegicus | |||
13. | ALA3219143 | 10, PF-4776548 | PPB | = | 92 | % | ALA3226542 | % | ||||
14. | ALA3219143 | 10, PF-4776548 | PPB | = | 84 | % | ALA3226543 | % | ||||
15. | ALA3219143 | 10, PF-4776548 | PPB | = | 91 | % | ALA3226544 | % | ||||
16. | ALA3219143 | 10, PF-4776548 | CLH | = | 17 | uL/min | ALA3226545 | uL/min | ||||
17. | ALA3219143 | 10, PF-4776548 | CLH | = | 33 | uL/min | ALA3226546 | uL/min | Rattus norvegicus | |||
18. | ALA3219143 | 10, PF-4776548 | CLH | = | 21 | uL/min | ALA3226547 | uL/min | Canis lupus familiaris | |||
19. | ALA3219143 | 10, PF-4776548 | CLH | = | 43 | uL/min | ALA3226548 | uL/min | Rattus norvegicus | |||
20. | ALA3219143 | 10, PF-4776548 | CLH | = | 26 | uL/min | ALA3226549 | uL/min | Rattus norvegicus |