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# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3219283 | 3, HYDAMTIQ | INH | = | 14 | % | ALA3223442 | % | Homo sapiens | |||
2. | ALA3219283 | 3, HYDAMTIQ | Drug uptake(free) | = | 87 | nM | ALA3223441 | nM | Rattus norvegicus | |||
3. | ALA3219283 | 3, HYDAMTIQ | Fu | = | 13 | % | ALA3223440 | |||||
4. | ALA3219283 | 3, HYDAMTIQ | Cmax | = | 678 | nM | ALA3223439 | nM | Rattus norvegicus | |||
5. | ALA3219283 | 3, HYDAMTIQ | BPR | = | 0.26 | ALA3223438 | ||||||
6. | ALA3219283 | 3, HYDAMTIQ | t1/2 | = | 0.8 | hr | ALA3223201 | hr | Rattus norvegicus | |||
7. | ALA3219283 | 3, HYDAMTIQ | AUC | = | 1680 | hr.ng/ml | ALA3223200 | ng.hr.mL-1 | Rattus norvegicus | |||
8. | ALA3219283 | 3, HYDAMTIQ | Vd | = | 2.1 | L/Kg | ALA3223199 | L.kg-1 | Rattus norvegicus | |||
9. | ALA3219283 | 3, HYDAMTIQ | CL | = | 69 | uL/min/kg | ALA3223198 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA3219283 | 3, HYDAMTIQ | CLH | = | 22.2 | uL/min | ALA3223197 | uL/min | Homo sapiens | |||
11. | ALA3219283 | 3, HYDAMTIQ | CLH | = | 26.4 | uL/min | ALA3223196 | uL/min | Rattus norvegicus | |||
12. | ALA3219283 | 3, HYDAMTIQ | t1/2 | = | 30 | min | ALA3225214 | hr | Homo sapiens | |||
13. | ALA3219283 | 3, HYDAMTIQ | t1/2 | = | 3 | min | ALA3225213 | hr | Rattus norvegicus | |||
14. | ALA3219283 | 3, HYDAMTIQ | IC50 | < | 200 | uM | ALA3225212 | nM | Homo sapiens | |||
15. | ALA3219283 | 3, HYDAMTIQ | IC50 | = | 170 | uM | ALA3225211 | nM | Homo sapiens | |||
16. | ALA3219283 | 3, HYDAMTIQ | IC50 | < | 200 | uM | ALA3225210 | nM | Homo sapiens | |||
17. | ALA3219283 | 3, HYDAMTIQ | permeability | = | 4.6 | ucm/s | ALA3225209 | ucm/s | ||||
18. | ALA3219283 | 3, HYDAMTIQ | Kinetic_solubility | = | 70 | ug ml-1 | ALA3225203 | ug.mL-1 | ||||
19. | ALA3219283 | 3, HYDAMTIQ | INH | = | 42 | % | ALA3225208 | % | Rattus norvegicus | |||
20. | ALA3219283 | 3, HYDAMTIQ | INH | = | 62 | % | ALA3225207 | % | Rattus norvegicus |