# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3219804 | Scheme 2, R3C2 | IC50 | = | 0.455 | uM | ALA3227821 | 6.34 | nM | |||
2. | ALA3219804 | Scheme 2, R3C2 | MIC | = | 12 | ug ml-1 | ALA3227817 | ug.mL-1 | Bacillus anthracis | |||
3. | ALA3219804 | Scheme 2, R3C2 | Stability | 0 | ALA3529131 | Stable | % | |||||
4. | ALA3219804 | Scheme 2, R3C2 | Stability | 0 | ALA3530755 | Stable | % | |||||
5. | ALA3219804 | Scheme 2, R3C2 | Stability | 0 | ALA3530754 | Stable | % | |||||
6. | ALA3219804 | Scheme 2, R3C2 | Drug metabolism | = | 15.1 | % | ALA3530753 | % | ||||
7. | ALA3219804 | Scheme 2, R3C2 | Drug metabolism | = | 5.3 | % | ALA3530752 | % | ||||
8. | ALA3219804 | Scheme 2, R3C2 | Drug metabolism | = | 6.3 | % | ALA3530569 | % | ||||
9. | ALA3219804 | Scheme 2, R3C2 | Drug metabolism | = | 70.5 | % | ALA3530568 | % | ||||
10. | ALA3219804 | Scheme 2, R3C2 | t1/2 | < | 10 | min | ALA3530567 | hr | Mus musculus | |||
11. | ALA3219804 | Scheme 2, R3C2 | Stability | = | 0 | % | ALA3530566 | % | Mus musculus | |||
12. | ALA3219804 | Scheme 2, R3C2 | MIC | = | 0.04 | ug ml-1 | ALA3530564 | ug.mL-1 | Staphylococcus aureus | |||
13. | ALA3219804 | Scheme 2, R3C2 | IC50 | = | 12 | nM | ALA3530563 | 7.92 | nM | Staphylococcus aureus | ||
14. | ALA3219804 | Scheme 2, R3C2 | IC50 | = | 12 | nM | ALA3705794 | 7.92 | 267752 | nM | Staphylococcus aureus | |
15. | ALA3219804 | Scheme 2, R3C2 | IC50 | = | 61 | nM | ALA3707851 | 7.21 | 267793 | nM | Homo sapiens | |
16. | ALA3219804 | Scheme 2, R3C2 | IC50 | = | 28 | nM | ALA3707492 | 7.55 | 267778 | nM | Streptococcus pyogenes |