# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3221256 | meayamycin B | IC50 | = | 0.55 | nM | ALA5151314 | 9.26 | nM | Homo sapiens | ||
2. | ALA3221256 | meayamycin B | IC50 | = | 0.49 | nM | ALA5151313 | 9.31 | nM | Homo sapiens | ||
3. | ALA3221256 | meayamycin B | IC50 | = | 7.8 | nM | ALA5151312 | 8.11 | nM | Mus musculus | ||
4. | ALA3221256 | meayamycin B | Activity | 0 | ALA3226081 | Not Active | Homo sapiens | |||||
5. | ALA3221256 | meayamycin B | Activity | 0 | ALA3226080 | Toxic | Mus musculus | |||||
6. | ALA3221256 | meayamycin B | Activity | 0 | ALA3226078 | Toxic | Mus musculus | |||||
7. | ALA3221256 | meayamycin B | Activity | 0 | ALA3226073 | Non-toxic | Mus musculus | |||||
8. | ALA3221256 | meayamycin B | MTD | = | 0.5 | mg kg-1 | ALA3226076 | mg kg-1 | Mus musculus | |||
9. | ALA3221256 | meayamycin B | INH | = | 41 | % | ALA3226083 | % | Homo sapiens | |||
10. | ALA3221256 | meayamycin B | INH | = | 26 | % | ALA3226085 | % | Homo sapiens | |||
11. | ALA3221256 | meayamycin B | INH | = | 15 | % | ALA3226086 | % | Mus musculus | |||
12. | ALA3221256 | meayamycin B | t1/2 | = | 13 | hr | ALA3226094 | hr | Mus musculus | |||
13. | ALA3221256 | meayamycin B | Activity | = | 11 | % | ALA3226075 | % | Mus musculus | |||
14. | ALA3221256 | meayamycin B | Cp | < | 10 | ng/ml | ALA3226087 | ng/ml | Mus musculus | |||
15. | ALA3221256 | meayamycin B | Activity | = | 10 | % | ALA3226077 | % | Mus musculus | |||
16. | ALA3221256 | meayamycin B | Activity | = | 6 | % | ALA3226079 | % | Mus musculus |