# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3233872 | 7 | IC50 | = | 3 | uM | ALA3294184 | 5.52 | nM | Homo sapiens | ||
2. | ALA3233872 | 7 | IC50 | > | 50 | uM | ALA3294182 | nM | Homo sapiens | |||
3. | ALA3233872 | 7 | IC50 | = | 37 | nM | ALA3294188 | 7.43 | nM | Homo sapiens | ||
4. | ALA3233872 | 7 | permeability | = | 170 | nm/s | ALA3293945 | nm/s | Homo sapiens | |||
5. | ALA3233872 | 7 | Selectivity ratio | = | 100 | ALA3293944 | ||||||
6. | ALA3233872 | 7 | Selectivity ratio | = | 100 | ALA3293943 | ||||||
7. | ALA3233872 | 7 | Drug metabolism | = | 40 | % | ALA3294181 | % | Homo sapiens | |||
8. | ALA3233872 | 7 | solubility | = | 20 | uM | ALA3293946 | nM | ||||
9. | ALA3233872 | 7 | CLH | = | 7.6 | uL/min | ALA3293948 | uL/min | Homo sapiens | |||
10. | ALA3233872 | 7 | CLH | = | 3.9 | uL/min | ALA3293947 | uL/min | Rattus norvegicus | |||
11. | ALA3233872 | 7 | FC | = | 3 | ALA3293949 | Homo sapiens | |||||
12. | ALA3233872 | 7 | INH | = | 45 | % | ALA3294180 | % | Mus musculus | |||
13. | ALA3233872 | 7 | Drug degradation | = | 40 | % | ALA3239100 | % | Homo sapiens | |||
14. | ALA3233872 | 7 | Activity | = | -45 | % | ALA3239095 | % | Mus musculus | |||
15. | ALA3233872 | 7 | IC50 | = | 3000 | nM | ALA3239093 | 5.52 | nM | Homo sapiens | ||
16. | ALA3233872 | 7 | IC50 | > | 50000 | nM | ALA3239092 | nM | Homo sapiens | |||
17. | ALA3233872 | 7 | IC50 | = | 37 | nM | ALA3239091 | 7.43 | nM | Homo sapiens |