# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3234446 | 2, K17F | EC50 | = | 1.9 | nM | ALA4401048 | 8.72 | nM | Homo sapiens | ||
2. | ALA3234446 | 2, K17F | Activity | = | -20 | mmHg | ALA4401049 | mmHg | Mus musculus | |||
3. | ALA3234446 | 2, K17F | Activity | 0 | ALA4401049 | Tde | Mus musculus | |||||
4. | ALA3234446 | 2, K17F | Time | < | 30 | min | ALA4401029 | hr | Homo sapiens | |||
5. | ALA3234446 | 2, K17F | Time | < | 30 | min | ALA4401030 | hr | Homo sapiens | |||
6. | ALA3234446 | 2, K17F | Km | = | 190 | uM | ALA4401031 | nM | Homo sapiens | |||
7. | ALA3234446 | 2, K17F | Kcat | = | 3.4 | /s | ALA4401032 | /s | Homo sapiens | |||
8. | ALA3234446 | 2, K17F | Kcat/Km | = | 1.8 | 10'4/Ms | ALA4401033 | 10'4/Ms | Homo sapiens | |||
9. | ALA3234446 | 2, K17F | Km | = | 97 | uM | ALA4401034 | nM | Homo sapiens | |||
10. | ALA3234446 | 2, K17F | Kcat | = | 13.7 | /s | ALA4401035 | /s | Homo sapiens | |||
11. | ALA3234446 | 2, K17F | Kcat/Km | = | 1.4 | 10'5/Ms | ALA4401036 | 10'5/Ms | Homo sapiens | |||
12. | ALA3234446 | 2, K17F | Vmax | = | 2.947 | micromol/min | ALA4401043 | micromol/min | Homo sapiens | |||
13. | ALA3234446 | 2, K17F | t1/2 | = | 0.4 | hr | ALA4401044 | hr | Homo sapiens | |||
14. | ALA3234446 | 2, K17F | t1/2 | = | 0.4 | hr | ALA4401045 | hr | Homo sapiens | |||
15. | ALA3234446 | 2, K17F | t1/2 | = | 0.02 | hr | ALA4401046 | hr | Homo sapiens | |||
16. | ALA3234446 | 2, K17F | IC50 | = | 0.025 | nM | ALA4401047 | 10.60 | nM | Rattus norvegicus | ||
17. | ALA3234446 | 2, K17F | Ki | = | 0.04 | 10'-3microM | ALA3242425 | 10.40 | nM | Homo sapiens | ||
18. | ALA3234446 | 2, K17F | INH | 0 | ALA3242431 | Dose-dependent effect | % | Rattus norvegicus | ||||
19. | ALA3234446 | 2, K17F | t1/2 | = | 4.6 | min | ALA3242433 | hr | Mus musculus | |||
20. | ALA3234446 | 2, K17F | Imax | = | 85 | % | ALA3242432 | % | Rattus norvegicus |