| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3234568 | 22e | EC50 | = | 0.003 | uM | ALA3239420 | 8.52 | nM | Homo sapiens | ||
| 2. | ALA3234568 | 22e | Activity | 0 | ALA3239498 | Active | Mus musculus | |||||
| 3. | ALA3234568 | 22e | FC | = | 3.5 | ALA3239496 | Mus musculus | |||||
| 4. | ALA3234568 | 22e | Efficacy | = | 100 | % | ALA3239495 | % | Mus musculus | |||
| 5. | ALA3234568 | 22e | Efficacy | = | 100 | % | ALA3239494 | % | Homo sapiens | |||
| 6. | ALA3234568 | 22e | Activity | 0 | ALA3239451 | Active | Mus musculus | |||||
| 7. | ALA3234568 | 22e | F | = | 24 | % | ALA3239442 | % | Mus musculus | |||
| 8. | ALA3234568 | 22e | t1/2 | = | 1.35 | hr | ALA3239441 | hr | Mus musculus | |||
| 9. | ALA3234568 | 22e | t1/2 | = | 0.36 | hr | ALA3239440 | hr | Mus musculus | |||
| 10. | ALA3234568 | 22e | Cmax | = | 1067 | nM | ALA3239439 | nM | Mus musculus | |||
| 11. | ALA3234568 | 22e | Cmax | = | 4521 | nM | ALA3239438 | nM | Mus musculus | |||
| 12. | ALA3234568 | 22e | Vdss | = | 1.6 | L/Kg | ALA3239437 | L.kg-1 | Mus musculus | |||
| 13. | ALA3234568 | 22e | CL | = | 62 | ml/min.kg | ALA3239436 | mL.min-1.kg-1 | Mus musculus | |||
| 14. | ALA3234568 | 22e | AUC | = | 2540 | nM.hr | ALA3239435 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 15. | ALA3234568 | 22e | AUC | = | 2667 | nM.hr | ALA3239434 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 16. | ALA3234568 | 22e | IC50 | > | 10 | uM | ALA3239433 | nM | Homo sapiens | |||
| 17. | ALA3234568 | 22e | IC50 | = | 4.7 | uM | ALA3239432 | 5.33 | nM | Homo sapiens | ||
| 18. | ALA3234568 | 22e | CLH | > | 500 | microL/min/mg | ALA3239431 | mL.min-1.g-1 | Rattus norvegicus | |||
| 19. | ALA3234568 | 22e | CLH | = | 289 | microL/min/mg | ALA3239430 | mL.min-1.g-1 | Homo sapiens | |||
| 20. | ALA3234568 | 22e | CLH | = | 214 | microL/min/mg | ALA3239429 | mL.min-1.g-1 | Mus musculus |
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