| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3236948 | 44, CRA-680 | CL | = | 18 | ml/min.kg | ALA3242824 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 2. | ALA3236948 | 44, CRA-680 | CL | = | 5.6 | ml/min.kg | ALA3242825 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 3. | ALA3236948 | 44, CRA-680 | CL | = | 6.1 | ml/min.kg | ALA3242822 | mL.min-1.kg-1 | Macaca mulatta | |||
| 4. | ALA3236948 | 44, CRA-680 | t1/2 | = | 2.7 | hr | ALA3242823 | hr | Rattus norvegicus | |||
| 5. | ALA3236948 | 44, CRA-680 | t1/2 | = | 3.4 | hr | ALA3242819 | hr | Canis lupus familiaris | |||
| 6. | ALA3236948 | 44, CRA-680 | t1/2 | = | 4.1 | hr | ALA3242820 | hr | Macaca mulatta | |||
| 7. | ALA3236948 | 44, CRA-680 | Vdss | = | 1.2 | L/Kg | ALA3242821 | L.kg-1 | Rattus norvegicus | |||
| 8. | ALA3236948 | 44, CRA-680 | Vdss | = | 0.7 | L/Kg | ALA3242818 | L.kg-1 | Canis lupus familiaris | |||
| 9. | ALA3236948 | 44, CRA-680 | Vdss | = | 0.95 | L/Kg | ALA3242817 | L.kg-1 | Macaca mulatta | |||
| 10. | ALA3236948 | 44, CRA-680 | AUC | = | 1676 | ng.hr.kg/ml/mg | ALA3242816 | ng.hr.kg/ml/mg | Rattus norvegicus | |||
| 11. | ALA3236948 | 44, CRA-680 | AUC | = | 9459 | ng.hr.kg/ml/mg | ALA3242815 | ng.hr.kg/ml/mg | Canis lupus familiaris | |||
| 12. | ALA3236948 | 44, CRA-680 | AUC | = | 19675 | ng.hr.kg/ml/mg | ALA3242813 | ng.hr.kg/ml/mg | Macaca mulatta | |||
| 13. | ALA3236948 | 44, CRA-680 | Cmax | = | 253 | ng/ml | ALA3242814 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 14. | ALA3236948 | 44, CRA-680 | Cmax | = | 2011 | ng/ml | ALA3242811 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 15. | ALA3236948 | 44, CRA-680 | Cmax | = | 2967 | ng/ml | ALA3242812 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Macaca mulatta | ||
| 16. | ALA3236948 | 44, CRA-680 | F | = | 20 | % | ALA3242810 | % | Rattus norvegicus | |||
| 17. | ALA3236948 | 44, CRA-680 | F | = | 32 | % | ALA3242809 | % | Canis lupus familiaris | |||
| 18. | ALA3236948 | 44, CRA-680 | F | = | 69 | % | ALA3242807 | % | Macaca mulatta | |||
| 19. | ALA3236948 | 44, CRA-680 | IC50 | = | 6 | nM | ALA3242797 | 8.22 | nM | Homo sapiens | ||
| 20. | ALA3236948 | 44, CRA-680 | IC50 | = | 8 | nM | ALA3242795 | 8.10 | nM | Homo sapiens |
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