| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3262462 | 4, TCA1 | CC50 | > | 10 | uM | ALA4296191 | Median N= 2; Maxinhib -6.0 Pct | nM | Homo sapiens | ||
| 2. | ALA3262462 | 4, TCA1 | HC10 | > | 10 | uM | ALA4296784 | Median N= 2; Maxinhib 0.6 Pct | uM | |||
| 3. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296184 | Median N= 2; Maxinhib 13.3 Pct | nM | Staphylococcus aureus | ||
| 4. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296188 | Median N= 2; Maxinhib 7.9 Pct | nM | Acinetobacter baumannii | ||
| 5. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296187 | Median N= 2; Maxinhib 27.2 Pct | nM | Pseudomonas aeruginosa | ||
| 6. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296186 | Median N= 2; Maxinhib 18.1 Pct | nM | Klebsiella pneumoniae | ||
| 7. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296185 | Median N= 2; Maxinhib 5.7 Pct | nM | Escherichia coli | ||
| 8. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296190 | N= 1; Maxinhib -16.5 Pct | nM | Cryptococcus neoformans | ||
| 9. | ALA3262462 | 4, TCA1 | MIC | > | 10 | uM | ALA4296189 | Median N= 2; Maxinhib 4.3 Pct | nM | Candida albicans | ||
| 10. | ALA3262462 | 4, TCA1 | Inhibition | 89.3 | % | ALA4513102 | Active | % | Naegleria gruberi | |||
| 11. | ALA3262462 | 4, TCA1 | IC50 | = | 0.1 | ug ml-1 | ALA4831718 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
| 12. | ALA3262462 | 4, TCA1 | Ratio | = | 32 | ALA4831717 | ||||||
| 13. | ALA3262462 | 4, TCA1 | MIC | = | 0.48 | ug ml-1 | ALA4831716 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 14. | ALA3262462 | 4, TCA1 | MIC | = | 0.96 | ug ml-1 | ALA4831715 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 15. | ALA3262462 | 4, TCA1 | MIC | = | 15.36 | ug ml-1 | ALA4831714 | ug.mL-1 | Mycobacterium tuberculosis | |||
| 16. | ALA3262462 | 4, TCA1 | Activity | = | 2.86 | deltalog10CFU | ALA4831713 | deltalog10CFU | Mycobacterium tuberculosis | |||
| 17. | ALA3262462 | 4, TCA1 | Activity | = | 4.24 | log10CFU | ALA4831711 | log10CFU | Mycobacterium tuberculosis | |||
| 18. | ALA3262462 | 4, TCA1 | CL | = | 10.6 | ml/min.kg | ALA4831709 | mL.min-1.kg-1 | ||||
| 19. | ALA3262462 | 4, TCA1 | MRT | = | 0.39 | hr | ALA4831708 | hr | ||||
| 20. | ALA3262462 | 4, TCA1 | AUC | = | 7912 | ng.hr/ml | ALA4831707 | ng.hr.mL-1 |
The page will load shortly, Thanks for your patience!