# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA430853 | 20 | Ratio IC50 | = | 15 | ALA4724288 | ||||||
2. | ALA430853 | 20 | IC50 | = | 7.6 | uM | ALA4724287 | 5.12 | nM | Homo sapiens | ||
3. | ALA430853 | 20 | IC50 | = | 0.5 | uM | ALA4724286 | 6.30 | nM | |||
4. | ALA430853 | 20 | Activity | 0 | ALA4338863 | Active | ||||||
5. | ALA430853 | 20 | Activity | = | 20 | % | ALA4338858 | % | Plasmodium falciparum | |||
6. | ALA430853 | 20 | IC50 | = | 66.6 | uM | ALA3368691 | 4.18 | nM | Homo sapiens | ||
7. | ALA430853 | 20 | IC50 | = | 27.2 | uM | ALA3368690 | 4.57 | nM | Homo sapiens | ||
8. | ALA430853 | 20 | IC50 | = | 81.4 | uM | ALA3368692 | 4.09 | nM | |||
9. | ALA430853 | 20 | IC50 | = | 11.9 | uM | ALA3368693 | 4.92 | nM | Homo sapiens | ||
10. | ALA430853 | 20 | IC50 | = | 18.4 | uM | ALA3368694 | 4.74 | nM | Homo sapiens | ||
11. | ALA430853 | 20 | IC50 | = | 60 | uM | ALA3875325 | 4.22 | nM | |||
12. | ALA430853 | 20 | IC50 | = | 30 | uM | ALA3875324 | 4.52 | nM | |||
13. | ALA430853 | 20 | IC50 | = | 30 | uM | ALA3875323 | 4.52 | nM | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ||
14. | ALA430853 | 20 | MIC | = | 0.5 | ug ml-1 | ALA2209279 | ug.mL-1 | Mycobacterium tuberculosis | |||
15. | ALA430853 | 20 | MIC | = | 0.5 | ug ml-1 | ALA2209280 | ug.mL-1 | Mycobacterium tuberculosis | |||
16. | ALA430853 | 20 | Selectivity Index | < | 8 | ALA2209281 | ||||||
17. | ALA430853 | 20 | Selectivity Index | < | 8 | ALA2209282 | ||||||
18. | ALA430853 | 20 | IC50 | = | 15.1 | nM | ALA3077583 | 7.82 | nM | Mycobacterium tuberculosis | ||
19. | ALA430853 | 20 | pIC50 | = | 1.179 | ALA3077583 | nM | Mycobacterium tuberculosis | ||||
20. | ALA430853 | 20 | log GI50 (M) | -5.448 | ALA1963976 | inactive | nM | Homo sapiens |