# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | Activity | = | 300 | mg kg-1 | ALA3285768 | mg kg-1 | Mus musculus | |||
2. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | ILS | = | 27 | % | ALA3285769 | % | Mus musculus | |||
3. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | IC50 | = | 14 | 10'-8M | ALA3285765 | 6.85 | nM | Lactobacillus casei | ||
4. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | GI50 | = | 10 | 10'-11M | ALA3285764 | nM | Lacticaseibacillus rhamnosus | |||
5. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | IC50 | = | 4 | uM | ALA3285766 | 5.40 | nM | Lactobacillus casei | ||
6. | ALA3273847 | 8, 8-methyl-7,8-dihydromethotrexate | ID50 | = | 0.23 | ug ml-1 | ALA3285767 | ug ml-1 | Homo sapiens |