# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3288030 | 12b | ED80 | = | 0.6 | ug/kg | ALA3295487 | ug/kg | Rattus norvegicus | |||
2. | ALA3288030 | 12b | ED80 | = | 78 | nM | ALA3295486 | nM | Rattus norvegicus | |||
3. | ALA3288030 | 12b | Activity | = | 123 | nM | ALA3295492 | nM | Rattus norvegicus | |||
4. | ALA3288030 | 12b | Activity | = | 88 | nM | ALA3295491 | nM | Rattus norvegicus | |||
5. | ALA3288030 | 12b | Activity | = | 26 | nM | ALA3295490 | nM | Rattus norvegicus | |||
6. | ALA3288030 | 12b | Activity | = | 9 | nM | ALA3295489 | nM | Rattus norvegicus | |||
7. | ALA3288030 | 12b | t1/2 | = | 15 | hr | ALA3295485 | hr | Canis lupus familiaris | |||
8. | ALA3288030 | 12b | F | = | 6 | % | ALA3295484 | % | Canis lupus familiaris | |||
9. | ALA3288030 | 12b | Vz/F | = | 25 | L/Kg | ALA3295483 | L.kg-1 | Canis lupus familiaris | |||
10. | ALA3288030 | 12b | Vdss | = | 13 | L/Kg | ALA3295228 | L.kg-1 | Canis lupus familiaris | |||
11. | ALA3288030 | 12b | CL | = | 19 | ml/min.kg | ALA3292513 | mL.min-1.kg-1 | Canis lupus familiaris | |||
12. | ALA3288030 | 12b | F | < | 16 | % | ALA3292512 | % | Rattus norvegicus | |||
13. | ALA3288030 | 12b | pIC50 | = | 5.2 | ALA3292514 | 5.20 | nM | Homo sapiens | |||
14. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3292517 | ||||||
15. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3292516 | ||||||
16. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3292519 | ||||||
17. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3292518 | ||||||
18. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3295227 | ||||||
19. | ALA3288030 | 12b | Selectivity ratio | > | 10000 | ALA3295226 | ||||||
20. | ALA3288030 | 12b | pIC50 | = | 10.6 | ALA3295225 | 10.60 | nM | Rattus norvegicus |