# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3288362 | 24 | EC50 | = | 20 | nM | ALA3428949 | 7.70 | nM | Homo sapiens | ||
2. | ALA3288362 | 24 | Drug metabolism | 0 | ALA3428950 | metabolite_detected | Homo sapiens | |||||
3. | ALA3288362 | 24 | EC50 | = | 20 | nM | ALA3607676 | 7.70 | nM | Homo sapiens | ||
4. | ALA3288362 | 24 | CL | = | 0.37 | L/hr/kg | ALA3607688 | mL.min-1.kg-1 | Rattus norvegicus | |||
5. | ALA3288362 | 24 | Vdss | = | 0.16 | L/Kg | ALA3607689 | L.kg-1 | Rattus norvegicus | |||
6. | ALA3288362 | 24 | t1/2 | = | 0.37 | hr | ALA3607690 | hr | Rattus norvegicus | |||
7. | ALA3288362 | 24 | Cmax | = | 3.3 | ug ml-1 | ALA3607694 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
8. | ALA3288362 | 24 | AUC | = | 5.3 | microg/hr/ml | ALA3607695 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA3288362 | 24 | F | = | 64 | % | ALA3607696 | % | Rattus norvegicus | |||
10. | ALA3288362 | 24 | AUC | = | 78 | ug.hr/ml | ALA3294329 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA3288362 | 24 | AUC | = | 19 | ug.hr/ml | ALA3294328 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA3288362 | 24 | AUC | = | 4.8 | ug.hr/ml | ALA3294327 | ng.hr.mL-1 | Rattus norvegicus | |||
13. | ALA3288362 | 24 | Cmax | = | 51 | ug ml-1 | ALA3294326 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
14. | ALA3288362 | 24 | Cmax | = | 14 | ug ml-1 | ALA3294325 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
15. | ALA3288362 | 24 | Cmax | = | 4.1 | ug ml-1 | ALA3294324 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
16. | ALA3288362 | 24 | Activity | 0 | ALA3294323 | Active | Rattus norvegicus | |||||
17. | ALA3288362 | 24 | FC | = | 3 | ALA3294322 | Rattus norvegicus | |||||
18. | ALA3288362 | 24 | Activity | 0 | ALA3294320 | Dose-dependent effect | Rattus norvegicus | |||||
19. | ALA3288362 | 24 | Activity | 0 | ALA3294319 | Dose-dependent effect | Mus musculus | |||||
20. | ALA3288362 | 24 | F | = | 64 | % | ALA3294065 | % | Rattus norvegicus |