# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3289023 | 15 | Ki | = | 2105 | nM | ALA3294777 | 5.68 | nM | Homo sapiens | ||
2. | ALA3289023 | 15 | Ki | = | 1625 | nM | ALA3294779 | 5.79 | nM | Homo sapiens | ||
3. | ALA3289023 | 15 | Ki | = | 516 | nM | ALA3294776 | 6.29 | nM | Bos taurus | ||
4. | ALA3289023 | 15 | Inhibition | = | 14 | % | ALA3294775 | % | Homo sapiens | |||
5. | ALA3289023 | 15 | Ki | = | 10 | nM | ALA3294545 | 8.00 | nM | Homo sapiens | ||
6. | ALA3289023 | 15 | EC50 | = | 1364 | nM | ALA3294311 | 5.87 | nM | |||
7. | ALA3289023 | 15 | EC50 | = | 200 | nM | ALA3294310 | 6.70 | nM | Homo sapiens | ||
8. | ALA3289023 | 15 | EC50 | = | 48 | nM | ALA3294312 | 7.32 | nM | Homo sapiens | ||
9. | ALA3289023 | 15 | Cmax | = | 487 | ng/ml | ALA3294550 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
10. | ALA3289023 | 15 | AUC | = | 1000 | ng.hr/ml | ALA3294552 | ng.hr.mL-1 | Mus musculus | |||
11. | ALA3289023 | 15 | IC50 | > | 30 | uM | ALA3294548 | nM | Homo sapiens | |||
12. | ALA3289023 | 15 | IC50 | > | 30 | uM | ALA3294547 | nM | Homo sapiens | |||
13. | ALA3289023 | 15 | IC50 | > | 30 | uM | ALA3294546 | nM | Homo sapiens | |||
14. | ALA3289023 | 15 | IC50 | > | 30 | uM | ALA3294317 | nM | Homo sapiens | |||
15. | ALA3289023 | 15 | solubility | = | 194 | uM | ALA3294316 | nM | ||||
16. | ALA3289023 | 15 | beta t1/2 | = | 1.6 | hr | ALA3294551 | hr | Mus musculus | |||
17. | ALA3289023 | 15 | Tmax | = | 0.27 | hr | ALA3294549 | hr | Mus musculus | |||
18. | ALA3289023 | 15 | Activity | = | 100 | % | ALA3294784 | % | Homo sapiens | |||
19. | ALA3289023 | 15 | Activity | = | 96 | % | ALA3294786 | % | Homo sapiens | |||
20. | ALA3289023 | 15 | Activity | = | 95 | % | ALA3294785 | % |