# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3298273 | 12c | Activity | 0 | ALA3372556 | Non-toxic | Rattus norvegicus | |||||
2. | ALA3298273 | 12c | Activity | 0 | ALA3372555 | Non-toxic | Rattus norvegicus | |||||
3. | ALA3298273 | 12c | Activity | 0 | ALA3372554 | Non-toxic | Rattus norvegicus | |||||
4. | ALA3298273 | 12c | Fu | = | 1522 | nM | ALA3379181 | nM | ||||
5. | ALA3298273 | 12c | Fu | = | 1228 | nM | ALA3379180 | nM | ||||
6. | ALA3298273 | 12c | Fu | = | 711 | nM | ALA3379179 | nM | ||||
7. | ALA3298273 | 12c | Fu | = | 209 | nM | ALA3379178 | nM | ||||
8. | ALA3298273 | 12c | Fu | = | 13 | nM | ALA3379177 | nM | ||||
9. | ALA3298273 | 12c | INH | = | 55 | % | ALA3379176 | % | Rattus norvegicus | |||
10. | ALA3298273 | 12c | INH | 0 | ALA3379175 | Dose-dependent effect | % | Rattus norvegicus | ||||
11. | ALA3298273 | 12c | Ratio | = | 1.7 | ALA3379174 | ||||||
12. | ALA3298273 | 12c | BPR | = | 1.67 | ALA3379173 | ||||||
13. | ALA3298273 | 12c | Fu | = | 332 | nM | ALA3379172 | nM | ||||
14. | ALA3298273 | 12c | Drug uptake | = | 16.6 | uM | ALA3379171 | uM | Rattus norvegicus | |||
15. | ALA3298273 | 12c | F | = | 75 | % | ALA3379169 | % | Rattus norvegicus | |||
16. | ALA3298273 | 12c | Tmax | = | 0.5 | hr | ALA3379168 | hr | Rattus norvegicus | |||
17. | ALA3298273 | 12c | Cmax | = | 3.36 | uM | ALA3379167 | nM | Rattus norvegicus | |||
18. | ALA3298273 | 12c | AUC | = | 6.2 | uM.hr | ALA3379166 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
19. | ALA3298273 | 12c | t1/2 | = | 0.3 | hr | ALA3379165 | hr | Rattus norvegicus | |||
20. | ALA3298273 | 12c | Vdss | = | 2.6 | L/Kg | ALA3379164 | L.kg-1 | Rattus norvegicus |