# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3298923 | 31 | Activity | 0 | ALA3299748 | Non-toxic | Rattus norvegicus | |||||
2. | ALA3298923 | 31 | Activity | 0 | ALA3299747 | Dose-dependent effect | Mus musculus | |||||
3. | ALA3298923 | 31 | F | = | 17 | % | ALA3299746 | % | Mus musculus | |||
4. | ALA3298923 | 31 | Tmax | = | 0.5 | hr | ALA3299745 | hr | Mus musculus | |||
5. | ALA3298923 | 31 | Cmax | = | 1272 | nM | ALA3299744 | nM | Mus musculus | |||
6. | ALA3298923 | 31 | AUC | = | 5595 | hr.nM | ALA3299581 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
7. | ALA3298923 | 31 | t1/2 | = | 3.64 | hr | ALA3299580 | hr | Mus musculus | |||
8. | ALA3298923 | 31 | Vdss | = | 4.07 | L/Kg | ALA3299579 | L.kg-1 | Mus musculus | |||
9. | ALA3298923 | 31 | CL | = | 39.3 | ml/min.kg | ALA3299578 | mL.min-1.kg-1 | Mus musculus | |||
10. | ALA3298923 | 31 | Activity | 0 | ALA3299577 | Active | Mus musculus | |||||
11. | ALA3298923 | 31 | Activity | = | 58.6 | % | ALA3299576 | % | Rattus norvegicus | |||
12. | ALA3298923 | 31 | D50 | = | 5.5 | mg kg-1 | ALA3299575 | mg kg-1 | Rattus norvegicus | |||
13. | ALA3298923 | 31 | F | = | 39 | % | ALA3299574 | % | Rattus norvegicus | |||
14. | ALA3298923 | 31 | Tmax | = | 0.5 | hr | ALA3299573 | hr | Rattus norvegicus | |||
15. | ALA3298923 | 31 | Cmax | = | 3531 | nM | ALA3299572 | nM | Rattus norvegicus | |||
16. | ALA3298923 | 31 | AUC | = | 9309 | hr.nM | ALA3299571 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
17. | ALA3298923 | 31 | t1/2 | = | 4.3 | hr | ALA3299569 | hr | Rattus norvegicus | |||
18. | ALA3298923 | 31 | Vdss | = | 2.39 | L/Kg | ALA3299566 | L.kg-1 | Rattus norvegicus | |||
19. | ALA3298923 | 31 | CL | = | 25.7 | ml/min.kg | ALA3299563 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA3298923 | 31 | INH | = | 100 | % | ALA3299561 | % | Homo sapiens |