# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3299022 | 39 | F | = | 4 | % | ALA3299574 | % | Rattus norvegicus | |||
2. | ALA3299022 | 39 | Tmax | = | 1 | hr | ALA3299573 | hr | Rattus norvegicus | |||
3. | ALA3299022 | 39 | Cmax | = | 98 | nM | ALA3299572 | nM | Rattus norvegicus | |||
4. | ALA3299022 | 39 | AUC | = | 384 | hr.nM | ALA3299571 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
5. | ALA3299022 | 39 | t1/2 | = | 1.1 | hr | ALA3299568 | hr | Rattus norvegicus | |||
6. | ALA3299022 | 39 | Vdss | = | 3.33 | L/Kg | ALA3299565 | L.kg-1 | Rattus norvegicus | |||
7. | ALA3299022 | 39 | CL | = | 50 | ml/min.kg | ALA3299562 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA3299022 | 39 | Ratio IC50 | > | 100 | ALA3299559 | ||||||
9. | ALA3299022 | 39 | Ratio IC50 | > | 100 | ALA3299558 | ||||||
10. | ALA3299022 | 39 | Ratio IC50 | > | 100 | ALA3299557 | ||||||
11. | ALA3299022 | 39 | INH | = | 100 | % | ALA3299556 | % | Homo sapiens | |||
12. | ALA3299022 | 39 | IC50 | = | 4.4 | uM | ALA3299556 | 5.36 | nM | Homo sapiens | ||
13. | ALA3299022 | 39 | IC50 | > | 30 | uM | ALA3299555 | nM | Homo sapiens | |||
14. | ALA3299022 | 39 | INH | = | 5 | % | ALA3299555 | % | Homo sapiens | |||
15. | ALA3299022 | 39 | INH | = | 99 | % | ALA3299554 | % | Homo sapiens | |||
16. | ALA3299022 | 39 | IC50 | = | 8.1 | uM | ALA3299554 | 5.09 | nM | Homo sapiens | ||
17. | ALA3299022 | 39 | INH | = | 100 | % | ALA3299553 | % | Mus musculus | |||
18. | ALA3299022 | 39 | IC50 | = | 0.104 | uM | ALA3299553 | 6.98 | nM | Mus musculus | ||
19. | ALA3299022 | 39 | INH | = | 99 | % | ALA3299552 | % | Rattus norvegicus | |||
20. | ALA3299022 | 39 | IC50 | = | 0.19 | uM | ALA3299552 | 6.72 | nM | Rattus norvegicus |