# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3321809 | 11d | Activity | <= | 16 | % | ALA3777629 | % | Mus musculus | |||
2. | ALA3321809 | 11d | INH | = | 80 | % | ALA3777627 | % | Homo sapiens | |||
3. | ALA3321809 | 11d | F | = | 25 | % | ALA3777626 | % | Mus musculus | |||
4. | ALA3321809 | 11d | AUClast | = | 493 | hr.ng/ml | ALA3777625 | ng.hr.mL-1 | Mus musculus | |||
5. | ALA3321809 | 11d | AUClast | = | 39 | hr.ng/ml | ALA3777624 | ng.hr.mL-1 | Mus musculus | |||
6. | ALA3321809 | 11d | t1/2 | = | 1.7 | hr | ALA3777623 | hr | Mus musculus | |||
7. | ALA3321809 | 11d | t1/2 | = | 1.7 | hr | ALA3777622 | hr | Mus musculus | |||
8. | ALA3321809 | 11d | Vdss | = | 1.6 | L/Kg | ALA3777621 | L.kg-1 | Mus musculus | |||
9. | ALA3321809 | 11d | CL | = | 42 | ml/min.kg | ALA3777620 | mL.min-1.kg-1 | Mus musculus | |||
10. | ALA3321809 | 11d | IC50 | = | 1.5 | uM | ALA3777618 | 5.82 | nM | Homo sapiens | ||
11. | ALA3321809 | 11d | IC50 | = | 0.007 | uM | ALA5141609 | 8.15 | nM | Homo sapiens | ||
12. | ALA3321809 | 11d | IC50 | > | 3 | uM | ALA5141607 | nM | Homo sapiens | |||
13. | ALA3321809 | 11d | IC50 | = | 3.7 | uM | ALA5141606 | 5.43 | nM | Homo sapiens | ||
14. | ALA3321809 | 11d | IC50 | = | 0.068 | uM | ALA5141600 | 7.17 | nM | Homo sapiens | ||
15. | ALA3321809 | 11d | Activity | = | 16.3 | % | ALA3364542 | % | Mus musculus | |||
16. | ALA3321809 | 11d | TGI | = | 81 | % | ALA3364541 | % | Homo sapiens | |||
17. | ALA3321809 | 11d | F | = | 25 | % | ALA3364540 | % | Mus musculus | |||
18. | ALA3321809 | 11d | AUClast | = | 493 | hr.ng/ml | ALA3364539 | ng.hr.mL-1 | Mus musculus | |||
19. | ALA3321809 | 11d | t1/2 | = | 1.7 | hr | ALA3364538 | hr | Mus musculus | |||
20. | ALA3321809 | 11d | AUClast | = | 392 | hr.ng/ml | ALA3364537 | ng.hr.mL-1 | Mus musculus |