| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3325606 | 11 | EC50 | = | 56 | nM | ALA3362086 | 7.25 | nM | Plasmodium yoelii | ||
| 2. | ALA3325606 | 11 | EC50 | = | 74 | nM | ALA3362085 | 7.13 | nM | Plasmodium falciparum | ||
| 3. | ALA3325606 | 11 | Activity | = | 80 | % | ALA3370061 | % | Plasmodium berghei | |||
| 4. | ALA3325606 | 11 | t1/2 | = | 0.62 | hr | ALA3370060 | hr | Mus musculus | |||
| 5. | ALA3325606 | 11 | CL | = | 39.7 | ml/min.kg | ALA3370059 | mL.min-1.kg-1 | Mus musculus | |||
| 6. | ALA3325606 | 11 | Vdss | = | 0.9 | L/Kg | ALA3370058 | L.kg-1 | Mus musculus | |||
| 7. | ALA3325606 | 11 | F | = | 51.6 | % | ALA3370057 | % | Mus musculus | |||
| 8. | ALA3325606 | 11 | t1/2 | = | 1.35 | hr | ALA3370056 | hr | Mus musculus | |||
| 9. | ALA3325606 | 11 | AUC | = | 11.14 | uM.hr | ALA3370055 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 10. | ALA3325606 | 11 | Tmax | = | 0.5 | hr | ALA3370054 | hr | Mus musculus | |||
| 11. | ALA3325606 | 11 | Cmax | = | 8.3 | uM | ALA3370053 | nM | Mus musculus | |||
| 12. | ALA3325606 | 11 | t1/2 | = | 57 | min | ALA3370052 | hr | Mus musculus | |||
| 13. | ALA3325606 | 11 | ERH | = | 52 | % | ALA3370051 | % | ||||
| 14. | ALA3325606 | 11 | IC50 | = | 0.056 | uM | ALA3370046 | 7.25 | nM | Plasmodium falciparum | ||
| 15. | ALA3325606 | 11 | IC50 | = | 0.062 | uM | ALA3370047 | 7.21 | nM | Plasmodium yoelii | ||
| 16. | ALA3325606 | 11 | IC50 | = | 0.19 | uM | ALA3370048 | 6.72 | nM | Plasmodium cynomolgi | ||
| 17. | ALA3325606 | 11 | IC50 | = | 0.26 | uM | ALA3370049 | 6.58 | nM | Plasmodium cynomolgi | ||
| 18. | ALA3325606 | 11 | solubility | = | 170 | uM | ALA3370050 | nM |
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