# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3325894 | 52ae | INH | = | 72 | % | ALA5126982 | % | Rattus norvegicus | |||
2. | ALA3325894 | 52ae | IC50 | = | 0.043 | uM | ALA5126980 | 7.37 | nM | |||
3. | ALA3325894 | 52ae | IC50 | = | 0.025 | uM | ALA5126979 | 7.60 | nM | |||
4. | ALA3325894 | 52ae | INH | = | 88 | % | ALA5126978 | % | Rattus norvegicus | |||
5. | ALA3325894 | 52ae | IC50 | = | 0.025 | uM | ALA3396094 | 7.60 | nM | Homo sapiens | ||
6. | ALA3325894 | 52ae | IC50 | = | 0.043 | uM | ALA3396093 | 7.37 | nM | Rattus norvegicus | ||
7. | ALA3325894 | 52ae | ED50 | = | 0.95 | mg kg-1 | ALA3361777 | mg.kg-1 | Rattus norvegicus | |||
8. | ALA3325894 | 52ae | INH | = | 50 | % | ALA3361778 | % | Rattus norvegicus | |||
9. | ALA3325894 | 52ae | INH | 0 | ALA3361777 | Dose-dependent effect | % | Rattus norvegicus | ||||
10. | ALA3325894 | 52ae | Activity | = | 35 | % | ALA3361775 | % | Homo sapiens | |||
11. | ALA3325894 | 52ae | CLH | = | 0.05 | ml/hr | ALA3361774 | ml/hr | Homo sapiens | |||
12. | ALA3325894 | 52ae | Drug metabolism | = | 3 | % | ALA3361773 | % | Mus musculus | |||
13. | ALA3325894 | 52ae | Drug metabolism | = | 13 | % | ALA3361769 | % | Rattus norvegicus | |||
14. | ALA3325894 | 52ae | Drug metabolism | = | 59 | % | ALA3361768 | % | Homo sapiens | |||
15. | ALA3325894 | 52ae | permeability | = | 1 | 10'-7 cm/s | ALA3367080 | 10'-7 cm/s | ||||
16. | ALA3325894 | 52ae | IC50 | = | 0.02 | uM | ALA3367079 | 7.70 | nM | Rattus norvegicus | ||
17. | ALA3325894 | 52ae | IC50 | = | 7 | nM | ALA3367077 | 8.15 | nM | Homo sapiens |