# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3326188 | 7l | INH | 0 | ALA3372723 | Active | % | Rattus norvegicus | ||||
2. | ALA3326188 | 7l | INH | 0 | ALA3372722 | Active | % | Rattus norvegicus | ||||
3. | ALA3326188 | 7l | F | = | 37 | % | ALA3372721 | % | Rattus norvegicus | |||
4. | ALA3326188 | 7l | t1/2 | = | 6.1 | hr | ALA3372720 | hr | Rattus norvegicus | |||
5. | ALA3326188 | 7l | Cmax | = | 411 | ng/ml | ALA3372719 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
6. | ALA3326188 | 7l | Vdss | = | 0.59 | L/Kg | ALA3372718 | L.kg-1 | Rattus norvegicus | |||
7. | ALA3326188 | 7l | t1/2 | = | 5.9 | hr | ALA3372717 | hr | Rattus norvegicus | |||
8. | ALA3326188 | 7l | CL | = | 0.28 | ml/min.kg | ALA3372716 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA3326188 | 7l | IC50 | > | 1000 | nM | ALA3372715 | nM | ||||
10. | ALA3326188 | 7l | IC50 | > | 1000 | nM | ALA3372714 | nM | Homo sapiens | |||
11. | ALA3326188 | 7l | IC50 | > | 1000 | nM | ALA3372713 | nM | Homo sapiens | |||
12. | ALA3326188 | 7l | IC50 | = | 292 | nM | ALA3372712 | 6.54 | nM | Homo sapiens | ||
13. | ALA3326188 | 7l | IC50 | = | 183 | nM | ALA3372168 | 6.74 | nM | |||
14. | ALA3326188 | 7l | IC50 | = | 5.3 | nM | ALA3372167 | 8.28 | nM | Rattus norvegicus | ||
15. | ALA3326188 | 7l | IC50 | = | 9.6 | uM | ALA3372166 | 5.02 | nM | Rattus norvegicus |