| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3326454 | 26 | Activity | 0 | ALA3372000 | Dose-dependent effect | Rattus norvegicus | |||||
| 2. | ALA3326454 | 26 | Activity | 0 | ALA3371995 | Non-toxic | Rattus norvegicus | |||||
| 3. | ALA3326454 | 26 | Activity | 0 | ALA3371999 | Active | Rattus norvegicus | |||||
| 4. | ALA3326454 | 26 | ED50 | = | 2.73 | mg kg-1 | ALA3372001 | mg.kg-1 | Rattus norvegicus | |||
| 5. | ALA3326454 | 26 | ED50 | = | 0.07 | mg kg-1 | ALA3372000 | mg.kg-1 | Rattus norvegicus | |||
| 6. | ALA3326454 | 26 | F | = | 75 | % | ALA3371998 | % | Rattus norvegicus | |||
| 7. | ALA3326454 | 26 | AUC | = | 670 | ng.hr/ml | ALA3371997 | ng.hr.mL-1 | Rattus norvegicus | |||
| 8. | ALA3326454 | 26 | Cmax | = | 79 | ng/ml | ALA3371996 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 9. | ALA3326454 | 26 | Tmax | = | 1.5 | hr | ALA3371994 | hr | Rattus norvegicus | |||
| 10. | ALA3326454 | 26 | AUC | = | 708 | ng.hr/ml | ALA3371993 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA3326454 | 26 | Vd | = | 4.6 | L/Kg | ALA3371992 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA3326454 | 26 | beta t1/2 | = | 5.7 | hr | ALA3371991 | hr | Rattus norvegicus | |||
| 13. | ALA3326454 | 26 | CL | = | 1.7 | l/hr.kg | ALA3371990 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA3326454 | 26 | IC50 | > | 1000 | nM | ALA3371989 | nM | Homo sapiens | |||
| 15. | ALA3326454 | 26 | IC50 | = | 700 | nM | ALA3371988 | 6.16 | nM | Homo sapiens | ||
| 16. | ALA3326454 | 26 | IC50 | > | 1000 | nM | ALA3371987 | nM | Homo sapiens | |||
| 17. | ALA3326454 | 26 | IC50 | = | 0.7 | nM | ALA3371986 | 9.15 | nM | Homo sapiens | ||
| 18. | ALA3326454 | 26 | Drug uptake | 0 | ALA3371985 | Not Active | ||||||
| 19. | ALA3326454 | 26 | permeability | 0 | ALA3371984 | permeable | ||||||
| 20. | ALA3326454 | 26 | Jss | = | 2 | ug/cm2.hr | ALA3371983 | ug/cm2.hr | Homo sapiens |
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