| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3326639 | 11aA | INH | 0 | ALA3372600 | Active | % | Plasmodium chabaudi | ||||
| 2. | ALA3326639 | 11aA | INH | 0 | ALA3372599 | Active | % | Plasmodium chabaudi | ||||
| 3. | ALA3326639 | 11aA | INH | 0 | ALA3372598 | Dose-dependent effect | % | Plasmodium chabaudi | ||||
| 4. | ALA3326639 | 11aA | ED50 | = | 0.12 | mg kg-1 | ALA3372598 | mg.kg-1 | Plasmodium chabaudi | |||
| 5. | ALA3326639 | 11aA | t1/2 | = | 5.78 | hr | ALA3372597 | hr | Rattus norvegicus | |||
| 6. | ALA3326639 | 11aA | t1/2 | = | 6.36 | hr | ALA3372596 | hr | Rattus norvegicus | |||
| 7. | ALA3326639 | 11aA | AUC | = | 26.6 | ug/ml.hr | ALA3372595 | ng.hr.mL-1 | Rattus norvegicus | |||
| 8. | ALA3326639 | 11aA | AUC | = | 8.2 | ug/ml.hr | ALA3372594 | ng.hr.mL-1 | Rattus norvegicus | |||
| 9. | ALA3326639 | 11aA | Cmax | = | 3.07 | ug ml-1 | ALA3372593 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3326639 | 11aA | Cmax | = | 1.03 | ug ml-1 | ALA3372592 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 11. | ALA3326639 | 11aA | Tmax | = | 4 | hr | ALA3372591 | hr | Rattus norvegicus | |||
| 12. | ALA3326639 | 11aA | Tmax | = | 3.4 | hr | ALA3372590 | hr | Rattus norvegicus | |||
| 13. | ALA3326639 | 11aA | Stability | = | 81.6 | % | ALA3372589 | % | Mus musculus | |||
| 14. | ALA3326639 | 11aA | Stability | = | 89 | % | ALA3372588 | % | Homo sapiens | |||
| 15. | ALA3326639 | 11aA | Activity | 0 | ALA3372587 | Active | Plasmodium falciparum | |||||
| 16. | ALA3326639 | 11aA | Activity | 0 | ALA3372586 | Active | Plasmodium falciparum | |||||
| 17. | ALA3326639 | 11aA | Activity | 0 | ALA3372585 | Active | Plasmodium falciparum | |||||
| 18. | ALA3326639 | 11aA | Activity | 0 | ALA3372584 | Active | Plasmodium falciparum | |||||
| 19. | ALA3326639 | 11aA | Ratio CC50/EC50 | > | 1000 | ALA3372014 | ||||||
| 20. | ALA3326639 | 11aA | EC50 | = | 80 | nM | ALA3372013 | 7.10 | nM | Plasmodium falciparum |
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