| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3327077 | 19 | Tmax | = | 1 | hr | ALA3371014 | hr | Rattus norvegicus | |||
| 2. | ALA3327077 | 19 | t1/2 | = | 3.5 | hr | ALA3371013 | hr | Rattus norvegicus | |||
| 3. | ALA3327077 | 19 | Cmax | = | 890 | nM | ALA3371012 | nM | Rattus norvegicus | |||
| 4. | ALA3327077 | 19 | AUC | = | 12000 | nM.hr | ALA3371011 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 5. | ALA3327077 | 19 | t1/2 | = | 16.8 | min | ALA3371010 | hr | Rattus norvegicus | |||
| 6. | ALA3327077 | 19 | IC50 | = | 13.3 | nM | ALA3371009 | 7.88 | nM | Rattus norvegicus | ||
| 7. | ALA3327077 | 19 | Ratio Ki | > | 10000 | ALA3371008 | ||||||
| 8. | ALA3327077 | 19 | Activity | = | 103 | % | ALA3371007 | % | ||||
| 9. | ALA3327077 | 19 | Activity | = | 73.4 | % | ALA3371006 | % | Homo sapiens | |||
| 10. | ALA3327077 | 19 | PPB | = | 89 | % | ALA3371005 | % | Homo sapiens | |||
| 11. | ALA3327077 | 19 | INH | = | 32.5 | % | ALA3371004 | % | Homo sapiens | |||
| 12. | ALA3327077 | 19 | Tmax | = | 5 | hr | ALA3370769 | hr | Mus musculus | |||
| 13. | ALA3327077 | 19 | logP | = | 3.56 | ALA3371019 | ||||||
| 14. | ALA3327077 | 19 | solubility | = | 27 | ug ml-1 | ALA3361514 | ug.mL-1 | ||||
| 15. | ALA3327077 | 19 | Ki | = | 0.31 | nM | ALA3361515 | 9.51 | nM | Homo sapiens | ||
| 16. | ALA3327077 | 19 | t1/2 | = | 18.8 | min | ALA3361516 | hr | Homo sapiens | |||
| 17. | ALA3327077 | 19 | AUC | = | 19500 | nM.hr | ALA3370766 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 18. | ALA3327077 | 19 | Cmax | = | 900 | nM | ALA3370767 | nM | Mus musculus | |||
| 19. | ALA3327077 | 19 | t1/2 | = | 9 | hr | ALA3370768 | hr | Mus musculus |
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