| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3330060 | 8l | IC50 | 0 | ALA3370432 | Not Active | Homo sapiens | |||||
| 2. | ALA3330060 | 8l | IC50 | = | 56.49 | uM | ALA3370431 | 4.25 | nM | Homo sapiens | ||
| 3. | ALA3330060 | 8l | IC50 | = | 97.7 | uM | ALA3370430 | 4.01 | nM | Homo sapiens | ||
| 4. | ALA3330060 | 8l | IC50 | > | 40 | uM | ALA3370429 | nM | Homo sapiens | |||
| 5. | ALA3330060 | 8l | CL(app) | = | 22.8 | L/hr/kg | ALA3370421 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 6. | ALA3330060 | 8l | t1/2 | = | 2.74 | hr | ALA3370420 | hr | Rattus norvegicus | |||
| 7. | ALA3330060 | 8l | MRT | = | 2.81 | hr | ALA3370419 | hr | Rattus norvegicus | |||
| 8. | ALA3330060 | 8l | AUC | = | 2361 | ng/mL.hr | ALA3370418 | ng.hr.mL-1 | Rattus norvegicus | |||
| 9. | ALA3330060 | 8l | AUCt | = | 2040 | ng/mL.hr | ALA3370417 | ng.hr.mL-1 | Rattus norvegicus | |||
| 10. | ALA3330060 | 8l | Cmax | = | 509 | ng/ml | ALA3370416 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 11. | ALA3330060 | 8l | Tmax | = | 0.5 | hr | ALA3370415 | hr | Rattus norvegicus | |||
| 12. | ALA3330060 | 8l | F | = | 53.2 | % | ALA3370179 | % | Rattus norvegicus | |||
| 13. | ALA3330060 | 8l | t1/2 | = | 2.03 | hr | ALA3370177 | hr | Rattus norvegicus | |||
| 14. | ALA3330060 | 8l | MRT | = | 3.03 | hr | ALA3370176 | hr | Rattus norvegicus | |||
| 15. | ALA3330060 | 8l | AUC | = | 8935 | ng/mL.hr | ALA3370175 | ng.hr.mL-1 | Rattus norvegicus | |||
| 16. | ALA3330060 | 8l | AUCt | = | 8838 | ng/mL.hr | ALA3370174 | ng.hr.mL-1 | Rattus norvegicus | |||
| 17. | ALA3330060 | 8l | Cmax | = | 2692 | ng/ml | ALA3370173 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 18. | ALA3330060 | 8l | Tmax | = | 0.3 | hr | ALA3370172 | hr | Rattus norvegicus | |||
| 19. | ALA3330060 | 8l | Activity | 0 | ALA3370164 | Dose-dependent effect | Mus musculus | |||||
| 20. | ALA3330060 | 8l | AUC | = | 795 | mmol/L/min | ALA3370163 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus |
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