# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3337539 | 10 | Kd(app) | <= | 10 | nM | ALA3365183 | nM | Trypanosoma cruzi (strain CL Brener) | |||
2. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365174 | Active | ||||||
3. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365173 | Active | ||||||
4. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365172 | Active | Mus musculus | |||||
5. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365171 | Active | Mus musculus | |||||
6. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365170 | Active | Mus musculus | |||||
7. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365166 | Active | ||||||
8. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365165 | Active | ||||||
9. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365164 | Active | Mus musculus | |||||
10. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365163 | Active | Mus musculus | |||||
11. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365162 | Active | Mus musculus | |||||
12. | ALA3337539 | 10 | Drug uptake | 0 | ALA3365161 | Active | Mus musculus | |||||
13. | ALA3337539 | 10 | Drug uptake | 0 | ALA3366966 | Active | Mus musculus | |||||
14. | ALA3337539 | 10 | Activity | 0 | ALA3366951 | Non-toxic | Mus musculus | |||||
15. | ALA3337539 | 10 | EC50 | = | 6.8 | nM | ALA3366950 | 8.17 | nM | Trypanosoma cruzi | ||
16. | ALA3337539 | 10 | INH | = | 85 | % | ALA3366949 | % | Homo sapiens | |||
17. | ALA3337539 | 10 | INH | = | 57 | % | ALA3366948 | % | Homo sapiens | |||
18. | ALA3337539 | 10 | INH | = | 95 | % | ALA3366947 | % | Homo sapiens | |||
19. | ALA3337539 | 10 | INH | = | 6 | % | ALA3366946 | % | Homo sapiens | |||
20. | ALA3337539 | 10 | t1/2 | = | 33 | min | ALA3366945 | hr | Mus musculus |