| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3338195 | 8 | IC50 | = | 0.45 | uM | ALA3388019 | 6.35 | nM | Homo sapiens | ||
| 2. | ALA3338195 | 8 | INH | 0 | ALA3388018 | Dose-dependent effect | % | Homo sapiens | ||||
| 3. | ALA3338195 | 8 | INH | 0 | ALA3388017 | Dose-dependent effect | % | Homo sapiens | ||||
| 4. | ALA3338195 | 8 | Cmax | = | 519 | ug ml-1 | ALA3387448 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 5. | ALA3338195 | 8 | AUC | = | 2043 | ug/ml.hr | ALA3387447 | ng.hr.mL-1 | Rattus norvegicus | |||
| 6. | ALA3338195 | 8 | Vdss | = | 25 | L/Kg | ALA3387446 | L.kg-1 | Rattus norvegicus | |||
| 7. | ALA3338195 | 8 | CL | = | 5.9 | L/hr/kg | ALA3387445 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 8. | ALA3338195 | 8 | F | = | 28 | % | ALA3387444 | % | Rattus norvegicus | |||
| 9. | ALA3338195 | 8 | Cmax | = | 2938 | ug ml-1 | ALA3387443 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 10. | ALA3338195 | 8 | AUC | = | 1807 | ug/ml.hr | ALA3387442 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA3338195 | 8 | Vdss | = | 21 | L/Kg | ALA3387441 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA3338195 | 8 | CL | = | 1.2 | L/hr/kg | ALA3387440 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 13. | ALA3338195 | 8 | solubility | = | 8 | ug ml-1 | ALA3387438 | ug.mL-1 | ||||
| 14. | ALA3338195 | 8 | INH | 0 | ALA3387437 | Dose-dependent effect | % | Homo sapiens | ||||
| 15. | ALA3338195 | 8 | INH | 0 | ALA3387436 | Active | % | Homo sapiens | ||||
| 16. | ALA3338195 | 8 | INH | 0 | ALA3387435 | Active | % | Homo sapiens | ||||
| 17. | ALA3338195 | 8 | INH | 0 | ALA3387434 | Active | % | Homo sapiens | ||||
| 18. | ALA3338195 | 8 | INH | 0 | ALA3387433 | Active | % | Homo sapiens | ||||
| 19. | ALA3338195 | 8 | Activity | = | 3.54 | % | ALA3387432 | % | Homo sapiens | |||
| 20. | ALA3338195 | 8 | Activity | = | 34.72 | % | ALA3387431 | % | Homo sapiens |
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