| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3341854 | P26-BApc | INH | 0 | ALA3366760 | Active | % | Human immunodeficiency virus 1 | ||||
| 2. | ALA3341854 | P26-BApc | INH | 0 | ALA3366759 | Active | % | Human immunodeficiency virus 1 | ||||
| 3. | ALA3341854 | P26-BApc | IC50 | = | 8.31 | uM | ALA3366758 | 5.08 | nM | Human immunodeficiency virus 1 | ||
| 4. | ALA3341854 | P26-BApc | solubility | = | 18.2 | mg/ml | ALA3361460 | ug.mL-1 | ||||
| 5. | ALA3341854 | P26-BApc | t1/2 | = | 0.905 | hr | ALA3361458 | hr | ||||
| 6. | ALA3341854 | P26-BApc | t1/2 | = | 0.598 | hr | ALA3361459 | hr | Rattus norvegicus | |||
| 7. | ALA3341854 | P26-BApc | t1/2 | = | 0.815 | hr | ALA3361457 | hr | Rattus norvegicus | |||
| 8. | ALA3341854 | P26-BApc | Cmax | = | 40.4 | mg/ml | ALA3361456 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 9. | ALA3341854 | P26-BApc | Vd | = | 0.17 | L/Kg | ALA3361455 | L.kg-1 | Rattus norvegicus | |||
| 10. | ALA3341854 | P26-BApc | t1/2 | = | 3.13 | hr | ALA3361454 | hr | Rattus norvegicus | |||
| 11. | ALA3341854 | P26-BApc | MRT | = | 3.18 | hr | ALA3361453 | hr | Rattus norvegicus | |||
| 12. | ALA3341854 | P26-BApc | AUCt | = | 101 | ug/ml.hr | ALA3361452 | ng.hr.mL-1 | Rattus norvegicus | |||
| 13. | ALA3341854 | P26-BApc | Ratio EC50 | = | 10 | ALA3361451 | Human immunodeficiency virus 1 | |||||
| 14. | ALA3341854 | P26-BApc | Ratio EC50 | = | 11 | ALA3361450 | Human immunodeficiency virus 1 | |||||
| 15. | ALA3341854 | P26-BApc | Ratio EC50 | = | 6.5 | ALA3361449 | Human immunodeficiency virus 1 | |||||
| 16. | ALA3341854 | P26-BApc | Ratio EC50 | = | 1.2 | ALA3361448 | Human immunodeficiency virus 1 | |||||
| 17. | ALA3341854 | P26-BApc | Ratio EC50 | = | 4.6 | ALA3361447 | Human immunodeficiency virus 1 | |||||
| 18. | ALA3341854 | P26-BApc | EC50 | = | 308 | nM | ALA3361446 | 6.51 | nM | Human immunodeficiency virus 1 | ||
| 19. | ALA3341854 | P26-BApc | EC50 | = | 322 | nM | ALA3361445 | 6.49 | nM | Human immunodeficiency virus 1 | ||
| 20. | ALA3341854 | P26-BApc | EC50 | = | 192 | nM | ALA3361444 | 6.72 | nM | Human immunodeficiency virus 1 |
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