# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3342849 | 48 | IC50 | = | 5 | nM | ALA3388594 | 8.30 | nM | Homo sapiens | ||
2. | ALA3342849 | 48 | Stability | = | 87 | % | ALA3390407 | % | Cavia porcellus | |||
3. | ALA3342849 | 48 | Stability | = | 77 | % | ALA3390406 | % | Rattus norvegicus | |||
4. | ALA3342849 | 48 | Stability | = | 91 | % | ALA3390405 | % | Homo sapiens | |||
5. | ALA3342849 | 48 | AUClast | = | 1234 | hr.ng/ml | ALA3390403 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA3342849 | 48 | Cmax | = | 72 | ng/ml | ALA3390402 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA3342849 | 48 | Tmax | = | 24 | hr | ALA3390404 | hr | Rattus norvegicus | |||
8. | ALA3342849 | 48 | IC50 | = | 154 | nM | ALA3390401 | 6.81 | nM | Canis familiaris | ||
9. | ALA3342849 | 48 | IC50 | = | 161 | nM | ALA3390400 | 6.79 | nM | |||
10. | ALA3342849 | 48 | IC50 | = | 12 | nM | ALA3390399 | 7.92 | nM | |||
11. | ALA3342849 | 48 | INH | 0 | ALA3390398 | Active | % | Homo sapiens | ||||
12. | ALA3342849 | 48 | INH | 0 | ALA3390397 | Active | % | Homo sapiens | ||||
13. | ALA3342849 | 48 | INH | 0 | ALA3390396 | Active | % | Homo sapiens | ||||
14. | ALA3342849 | 48 | INH | 0 | ALA3390395 | Active | % | Homo sapiens | ||||
15. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3390394 | ||||||
16. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3389840 | ||||||
17. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3389839 | ||||||
18. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3389838 | ||||||
19. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3389837 | ||||||
20. | ALA3342849 | 48 | Selectivity ratio | > | 1000 | ALA3389836 |