| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3342955 | 11a | Vdss | = | 104 | ml/kg | ALA3404931 | L.kg-1 | Rattus norvegicus | |||
| 2. | ALA3342955 | 11a | AUC | = | 3.5 | ug.hr/ml | ALA3404930 | ng.hr.mL-1 | Rattus norvegicus | |||
| 3. | ALA3342955 | 11a | t1/2 | = | 3.4 | hr | ALA3404929 | hr | Rattus norvegicus | |||
| 4. | ALA3342955 | 11a | CL | = | 4.7 | ml/min.kg | ALA3404928 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 5. | ALA3342955 | 11a | F | = | 1.5 | % | ALA3404926 | % | Rattus norvegicus | |||
| 6. | ALA3342955 | 11a | AUC | = | 1.6 | ug.hr/ml | ALA3404767 | ng.hr.mL-1 | Rattus norvegicus | |||
| 7. | ALA3342955 | 11a | t1/2 | = | 3.2 | hr | ALA3404765 | hr | Rattus norvegicus | |||
| 8. | ALA3342955 | 11a | Cmax | = | 0.21 | ug ml-1 | ALA3404763 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
| 9. | ALA3342955 | 11a | Papp | = | 0.18 | 10'-6 cm/s | ALA3404760 | 10'-6 cm/s | ||||
| 10. | ALA3342955 | 11a | IC50 | = | 2.5 | nM | ALA3404759 | 8.60 | nM | Homo sapiens | ||
| 11. | ALA3342955 | 11a | IC50 | = | 11 | nM | ALA3404758 | 7.96 | nM | Homo sapiens | ||
| 12. | ALA3342955 | 11a | F | = | 1.5 | % | ALA3383963 | % | Rattus norvegicus | |||
| 13. | ALA3342955 | 11a | AUC | = | 1.6 | ug.hr/ml | ALA3383962 | ng.hr.mL-1 | Rattus norvegicus | |||
| 14. | ALA3342955 | 11a | IC50 | = | 0.011 | uM | ALA3389954 | 7.96 | nM | Homo sapiens | ||
| 15. | ALA3342955 | 11a | t1/2 | = | 3.4 | hr | ALA3390518 | hr | Rattus norvegicus | |||
| 16. | ALA3342955 | 11a | CL | = | 4.7 | ml/min.kg | ALA3390517 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 17. | ALA3342955 | 11a | IC50 | = | 0.003 | uM | ALA3390515 | 8.60 | nM | Homo sapiens | ||
| 18. | ALA3342955 | 11a | F | = | 1.5 | % | ALA3599425 | % | Rattus norvegicus | |||
| 19. | ALA3342955 | 11a | F | = | 2.8 | % | ALA3599424 | % | Cavia porcellus | |||
| 20. | ALA3342955 | 11a | INH | = | 0 | % | ALA3599423 | % | Cavia porcellus |
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